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Publication Extralevator abdominoperineal excision : our experience in a district general hospital(Wiley, 2015-09-23) Alyamani, A. A.; Hussain, S.; Piramanayagam, B.; Marimuthu, K.; Mathew, G.; George Eliot Hospital NHS Trust, Nuneaton; Colorectal Surgery; Medical and Dental; Alayamani, A. A.; Hussain, S.; Piramanayagam, B.; Marimuthu, K.; Mathew, G.Poster abstract P217 of the 10th Scientific and Annual Meeting of the European Society of Coloproctology, 23–25 September 2015, Dublin, Ireland.Publication Management of venothromboembolic disease in patients with newly diagnosed colorectal cancer(Wiley, 2015-09-23) Ayaani, S.; Vourvachis, M.; Yahia, S.; Marimuthu, K.; Piramanayagam, B.; George Eliot Hospital NHS Trust, Nuneaton; Colorectal Surgery; Medical and Dental; Ayaani, S.; Vourvachis, M.; Yahia, S.; Marimuthu, K.; Piramanayagam, B.Poster abstract P133 of the 10th Scientific and Annual Meeting of the European Society of Coloproctology, 23–25 September 2015, Dublin, Ireland.Publication Are we under-investigating possible venothromboembolic disease in newly diagnosed colorectal cancer?(Wiley, 2015-09-23) Ayaani, S.; Yahia, S.; Vourvachis, M.; Marimuthu, K.; Piramanayagam, B.; George Eliot Hospital NHS Trust, Nuneaton; Colorectal Surgery; Medical and Dental; Ayaani, S.; Yahia, S.; Vourvachis, M.; Marimuthu, K.; Piramanayagam, B.Poster abstract P134 of the 10th Scientific and Annual Meeting of the European Society of Coloproctology, 23–25 September 2015, Dublin, Ireland.Publication Our experience with colorectal cancer rate, Three years post colonoscopy(Wiley, 2018-09-04) Page, L.; Yahia, S.; Hero, E.; Hirri, F.; Narayanan, A.; George Eliot Hospital, Nuneaton; General Surgery; Colorectal Surgery; Medical and Dental; Page, L.; Yahia, S.; Hero, E.; Hirri, F.; Narayanan, A.Poster abstract P475 from the 13th Scientific and Annual Meeting of the European Society of Coloproctology, Nice, France, 26-28 September 2018.Publication Acute complicated diverticulitis—opportunity for conservative treatment(Wiley, 2019-09-24) John-Charles, R.; Yahia, S.; Jadhav, V.; Marimuthu, K.; Piramanayagam, B.; Narayanan, A.; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Colorectal Surgery; Medical and Dental; John-Charles, R.; Yahia, S.; Jadhav, V.; Marimuthu, K.; Piramanayagam, B.; Narayanan, A.Poster abstract P102 from the 14th Scientific and Annual Meeting of the European Society of Coloproctology, Austria Centre, 25-27 September 2019.Publication Risk of colorectal cancer and advanced adenomas in complicated diverticulitis – is there a concern?(Wiley, 2019-09-24) Yahia, S.; John-Charles, R.; Shahjahan, M.; Jadhav, V.; Piramanayagam, B.; Marimuthu, K.; Narayanan, A.; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Colorectal Surgery; Medical and Dental; Yahia, S.; John-Charles, R.; Shahjahan, M.; Jadhav, V.; Piramanayagam, B.; Marimuthu, K.; Narayanan, A.Poster abstract P110 from the 14th Scientific and Annual Meeting of the European Society of Coloproctology, Austria Centre, 25-27 September 2019.Publication Colonoscopy requests and follow-up appointments – evolving practice(Wiley, 2019-09-24) Wahedna, N.; Yahia, S.; Seretis, C.; John-Charles, R.; Siddiqui, Z.; Narayanan, A.; George Eliot Hospital, Nuneaton; General Surgery; Medical and Dental; Wahedna, N.; Yahia, S.; Seretis, C.; John-Charles, R.; Siddiqui, Z.; Narayanan, A.Poster abstract P087 from the 14th Scientific and Annual Meeting of the European Society of Coloproctology, Vienna, Austria, 25–27 September 2019.Publication Restrospective review of post colonoscopy colorectal cancer rates at the George Eliot Hospital Endoscopy Unit(Oxford University Press, 2020-06-24) Lim, P.; Yahia, S.; Newland, C.; Shah, W.; Narayanan, A.; George Eliot Hospital, Nuneaton; General Surgery; Medical and Dental; Lim, P.; Yahia, S.; Newland, C.; Shah, W.; Narayanan, A.Poster presentation abstract 429 from the Association of Surgeons in Training (ASiT) Annual Conference 6th-8th March 2020, Birmingham International Convention Centre.Publication Accuracy of intraoperative diagnosis of appendicitis in laparoscopy. Should this affect decision for appendicectomy(Oxford University Press, 2020-06-24) Gronroos, J.; Konstantinou, C.; George Eliot Hospital, Nuneaton; Good Hope Hospital, Birmingham; Warwick Hospital; Medical and Dental; Gronroos, J.Poster presentation abstract 942 from the Association of Surgeons in Training (ASiT) Annual Conference 6th-8th March 2020, Birmingham International Convention Centre.Publication A pandemic recap : lessons we have learned(BioMed Central, 2021-09-10) Coccolini, Federico; Cicuttin, Enrico; Cremonini, Camilla; Tartaglia, Dario; Viaggi, Bruno; Kuriyama, Akira; Picetti, Edoardo; Ball, Chad; Abu-Zidan, Fikri; Ceresoli, Marco; Turri, Bruno; Jain, Sumita; Palombo, Carlo; Guirao, Xavier; Rodrigues, Gabriel; Gachabayov, Mahir; Machado, Fernando; Eftychios, Lostoridis; S. Kanj, Souha; Di. Carlo, Isidoro; Di. Saverio, Salomone; Khokha, Vladimir; Kirkpatrick, Andrew; Massalou, Damien; Forfori, Francesco; Corradi, Francesco; Delibegovic, Samir; M. Machain Vega, Gustavo; Fantoni, Massimo; Demetriades, Demetrios; Kapoor, Garima; Kluger, Yoram; Ansari, Shamshul; Maier, Ron; Leppaniemi, Ari; Hardcastle, Timothy; Vereczkei, Andras; Karamagioli, Evika; Pikoulis, Emmanouil; Pistello, Mauro; E. Sakakushev, Boris; H. Navsaria, Pradeep; Galeiras, Rita; I. Yahya, Ali; V. Osipov, Aleksei; Dimitrov, Evgeni; Doklestic, Krstina; Pisano, Michele; Malacarne, Paolo; Carcoforo, Paolo; Grazia Sibilla, Maria; A. Kryvoruchko, Igor; Bonavina, Luigi; II. Kim, Jae; G. Shelat, Vishal; Czepiel, Jacek; Maseda, Emilio; Marwah, Sanjay; Chirica, Micrea; Biancofiore, Giandomenico; Podda, Mauro; Cobianchi, Lorenzo; Ansaloni, Luca; Fugazzola, Paola; Seretis, Charalampos; Augusto Gomez, Carlos; Tumietto, Fabio; Malbrain, Manu; Reichert, Martin; Augustin, Goran; Amato, Bruno; Puzziello, Alessandro; Hecker, Andreas; Gemignani, Angelo; Isik, Arda; Alessandro, Cucchetti; Nacoti, Micro; Kopelman, Doron; Mesina, Cristian; Ghannam, Wagih; Ben-Ishay, Offir; Dhingra, Sameer; Coimbra, Raul; E. Moore, Ernest; Cui, Yunfeng; A. Quiodettis, Martha; Bala, Miklosh; Testini, Mario; Diaz, Jose; Girardis, Massimo; L. Biffl, Walter; Hecker, Matthias; Sall, Ibrahima; Boggi, Ugo; Materazzi, Gabriele; Ghiadoni, Lorenzo; Matsumoto, Junichi; P. Zuidema, Wietse; Ivatury, Rao; A. Enani, Mushira; Litvin, Andrey; N. AI-Hasan, Majdi; Demetrashvili, Zaza; Baraket, Oussama; A. Ordonez, Carlos; Negoi, Ionut; Kiguba, Ronald; A. Memish, Ziad; M. Elmangory, Mutasim; Tolonen, Matti; Das, Korey; Ribeiro, Julival; O'Connor, Donal B.; Tan, Boun. K; Goor, Harry V.; Baral, Suman; Simone, Belinda De; Corbella, Davide; Brambillasca, Pietro; Scaglione, Michelangelo; Basolo, Fulvio; De'Angelis, Nicola; Bendinelli, Cino; Weber, Dieter; Pagani, Leonardo; Monti, Cinzia; Baiocchi, Gianluca; Chiarugi, Massimo; Catena, Fausto; Sartelli, Massimo; Pisa University Hospital, Italy; Careggi Hospital, Florence, Italy; Kurashiki Central Hospital, Japan; George Eliot Hospital, Nuneaton; et al.; General Surgery; Medical and Dental; Seretis, CharalamposOn January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white paper concerning the tough lessons we have learned from the COVID-19 pandemic. Thus, an international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making. With the present paper, international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making.Publication Percutaneous retroperitoneoscopic drainage of complex extraperitoneal abscesses using flexible endoscopy: description of technique and perioperative care(Editura Celsius, 2020-12) Seretis, Charalampos; Seretis, Fotios; Yahia, Shuker; Gill, Jagjit; Malik, Adnan; Zayyan, Kassim; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Seretis, Charalampos; Seretis, Fotios; Yahia, Shuker; Gill, Jagjit; Malik, Adnan; Zayyan, KassimThe treatment of primary psoas abscesses usually is performed by a combination of prolongued antiobiotic therapy and drainage with interventional radiology techniques. However, although this combination is usually adequate for the treatment of solitary extraperitoneal collections, the presence of multi-loculated complex abscesses requires usually multiple procedures and feruently mandates open surgery. Herein, we describe an alternative tehnique of percutaneous retroperitoneoscopic drainage of multiple extensive primary psoas abscesses using flexible endoscopy, which can enable treatment these cases as one-stop proedure in a minimally invasive manner.Publication Acute appendicitis in the context of undescended cecum: laparoscopic management with restoration of the orthotopic anatomy(Editura Celsius, 2022-06) Papageorgopoulou, Chrysanthi; Nikolakopoulos, Konstantinos; Seretis, Charalampos; University General Hospital of Patras, Greece; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Seretis, CharalamposUndescended cecum is a rare congenital abnormality; upon development of acute appendicitis though, the high position of the cecum results in atypical clinical symptomatology. We present a rare case of appendicitis in a patient with undescended cecum, which we managed laparoscopically, combining the appendicectomy with orthotopic repositioning of the cecum. Key words: laparoscopy, malrotation, undescended cecum, emergency, surgeryPublication Laparoscopic management of acutely symptomatic chylous mesenteric cyst(Editura Celsius, 2022-09) Zacharis, Georgios; Seretis, Charalampos; Zayyan, Kassim; General Hospital of Patras, Greece; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Seretis, Charalampos; Zayyan, KassimAcutely symptomatic chylous mesenteric cyst is a very rare cause of acute abdomen. We report a case of acutely inflamed chyle-containing benign mesenteric cyst, highlighting the role of laparoscopy as a safe diagnostic and therapeutic modality.Publication Should hospital readmissions be a key performance indicator in assessing a colorectal unit?(Wiley, 2022-09-13) Wu, T.-W.; Piramanayagam, B.; Marimuthu, K.; Haji, A.; Yahia, S.; George Eliot Hospital, Nuneaton; Colorectal Surgery; General Surgery; Medical and Dental; Wu, T.-W.; Piramanayagam, B.; Marimuthu, K.; Haji, A.; Yahia, S.Abstract P561 of the European Society of Colproctology 17th Scientific & Annual Meeting, 21 - 23 September 2022, Dublin, Ireland.Publication How well do endoscopic morphological and histopathological characteristics correlate in colonic polypectomy reporting?(Wiley, 2022-09) Piedad, J.; Yahia, S.; Tunstall, R.; Fayyad, M.; Deol, J.; Marimuthu, K.; George Eliot Hospital, Nuneaton; Colorectal Surgery; Medical and Dental; Piedad, J.; Yahia, S.; Tunstall, R.; Fayyad, M.; Deol, J.; Marimuthu, K.Abstract P384 of the ESCP 17th Scientific & Annual Meeting, 21-23 September 2022, Dublin, Ireland.Publication Ruscus extract, hesperidin methyl-chalcone and vitamin C, constituents of Cyclo 3 fort® in symptomatic chronic venous insufficiency: initial tertiary experience from southwestern Greece(Edizioni Minerva Medica, 2022-08) Papageorgopoulou, Chrysanthi; Papageorgopoulou, Aspasia; Seretis, Charalampos; Nikolakopoulos, Konstantinos; University General Hospital of Patras, Greece; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Seretis, CharalamposLetter to the Editor regarding an initial tertiary experience from southwestern Greece of ruscus extract, hesperidin methyl-chalcone and vitamin C, constituents of Cyclo 3 fort® in symptomatic chronic venous insufficiency.Publication Hyperthermic intraperitoneal chemotherapy with mitomycin C versus oxaliplatin after cytoreductive surgery for the treatment of peritoneal metastases of colorectal cancer origin(Editura Celsius, 2022-06) Papageorgopoulou, Chrysanthi; Nikolakopoulos, Konstantinos; Seretis, Charalampos; University General Hospital of Patras, Greece; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Seretis, CharalamposBackground: Mitomycin C and oxaliplatin are considered the main chemotherapeutic agents used in the context of hyperthermic intraperitoneal chemotherapy (HIPEC) after the performance of cytoreductive surgery for peritoneal metastases of colorectal cancer origin. However, there is lack of a generally accepted consensus regarding the optimal choice between them as upfront chemo-therapetic agent. Our paper aims to summarize in a comprehensive manner the available evidence, while individualised schemes with targeted therapies are under development. Methods: We conducted a comprehensive, narrative review of the literature including all previous studies until 03/2022, which reported perioperative and/ or oncological outcomes after the use of mitomycin C and/ or oxaliplatin as main hyperthermic chemotherapy agents after cytoreductive surgery for colorectal peritoneal metastatic disease. Results: Data from a total of 23 single-agent and 13 comparative studies were included in our review. Despite the demonstrated safety profile of both chemotherapeutics, the heterogeneity of the included studies, their retrospective nature and the absence of relevant randomized trials prohibits the drawing of safe conclusions regarding the superiority of one of the two agents. However, it seems that perioperative morbidity is less with oxaliplatin-based HIPEC, while mitomycin C appears as a more cost-effective option. Conclusions: Selection of the optimal intraperitoneal chemotherapy agent for peritoneal metastases of colorectal cancer origin after the completion of cytoreductive surgery is still a matter of debate, with significant institutional variation. Further randomized clinical trials between the two commonest HIPEC agents are required, assessing the differences in perioperative outcomes, oncological outcomes, healthcare-associated costs and patients' quality of life. Keywords: chemotherapy; cytoreduction; hyperthermia; mitomycin; oxaliplatin.Publication Is the increase in emergency colorectal cancer presentation directly related to the after effects of the pandemic?(Wiley, 2022-09) Sivakumar, N.; Roberts, L.; Marimuthu, K.; Piramanayagam, B.; George Eliot Hospital NHS Trust, Nuneaton; Colorectal Surgery; Medical and Dental; Sivakumar, N.; Roberts, L.; Marimuthu, K.; Piramanayagam, B.Poster abstract from the ESCP 17th Scientific & Annual Meeting, 21 - 23 September 2022, Dublin, Ireland.Publication Multiple synchronous intestinal tumors(De Gruyter, 2006-10-24) Nagpal, Kamal; Marimuthu, Kalimuthu; Mathew, George; Doncaster Royal Infirmary; George Eliot Hospital, Nuneaton; Surgery; Medical and Dental; Marimuthu, Kalimuthu; Mathew, GeorgeLetter to the Editor reporting the case of an 83-year-old woman with synchronous primary cancers of terminal ileum, sigmoid and upper rectum.Publication Auditing the routine microbiological examination of pus swabs from uncomplicated perianal abscesses: clinical necessity or old habit?(Elmer Press, 2020-06) Lalou, Lida; Archer, Lucy; Lim, Paul; Kretzmer, Leo; Elhassan, Ali Mohammed.; Awodiya, Afolabi; Seretis, Charalampos; George Eliot Hospital NHS Trust, Nuneaton; General Surgery; Medical and Dental; Lalou, Lida; Archer, Lucy; Lim, Paul; Kretzmer, Leo; Elhassan, Ali Mohammed.; Awodiya, Afolabi; Seretis, CharalamposBackground: Obtaining pus swabs from perianal abscesses after incision and drainage for subsequent microbiological analysis is traditionally performed by general surgeons. Our aim is to assess the current practice in our institution, emphasizing on whether pus swabs were sent or not, as well as to identify any associations between the revealed microbiology and the occurrence of immediate post-operative complications and re-admission rates with fistula-in-ano up to 12 months post the emergency drainage. Finally, we aimed to identify if the any members of the surgical team reviewed at any stage post-operatively the results of the microbiological examination of the obtained pus swabs and if that resulted in changes of the patient management. Methods: We reviewed the operative findings and perioperative antimicrobial management of all patients within our institution that required surgical treatment of perianal abscesses over a 6-week period and re-assessed them after 12 months from the performed drainage, with respect to re-admission and identification of occurred fistula-in-ano. Results: A total of 24 patients met our inclusion criteria. Pus swabs were sent in 66.7% of cases and only a third of the requested microbiology reports were reviewed by a part of the surgical team. All patients were discharged prior to the release of the microbiology results with no subsequent change in the management plan. We did not find any consistent association between the microbiology results and re-admission with perianal abscess, with or without fistula-in-ano. Conclusions: We do not recommend routine use of pus swabs when draining perianal abscesses unless clinical concerns arise, including recurrent perianal sepsis, immuno-compromised status or extensive soft tissue necrosis, especially when these features are associated with systemic sepsis.