Centre for Reproductive Medicine

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https://westmid.openrepository.com/handle/20.500.14200/1427

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    Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception.
    (Massachusetts Medical Society, 2019-03-23) Dhillon-Smith, Rima K; Middleton, Lee J; Sunner, Kirandeep K; Cheed, Versha; Baker, Krys; Farrell-Carver, Samantha; Bender-Atik, Ruth; Agrawal, Rina; Bhatia, Kalsang; Edi-Osagie, Edmond; Gupta, Pratima; Jurkovic, Davor; Khalaf, Yacoub; MacLean, Marjory; McCabe, Christopher; Mulbagal, Khashia; Nunes, Natalie; Overton, Caroline; Rai, Raj; Raine-Fenning, Nick; Robinson, Lynne; Ross, Jackie; Sizer, Andrew; Small, Rachel; Tan, Alex; Underwood, Martyn; Kilby, Mark D; Boelaert, Kristien; Daniels, Jane; Thangaratinam, Shakila; Chan, Shiao Y; Coomarasamy, Arri; Quenby, Siobhan; Ghobara, Tarek; Women's & Children's; Medical and Dental; Agrawal, Rina; Ghobara, Tarek; Quenby, Siobhan
    Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse outcomes.