Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire.
Chotai, Nikhil Yadav, Mahesh K Amarasena, Danuksha Kumar, Rohit
Chotai, Nikhil
Yadav, Mahesh
K Amarasena, Danuksha
Kumar, Rohit
Affiliation
University Hospitals of Leicester NHS Trust; The University of Manchester; The Dudley Group NHS Foundation Trust
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Publication date
2025-07-14
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Abstract
Objective This study aimed to assess whether a statistically significant correlation exists between socioeconomic status, measured by the Index of Multiple Deprivation (IMD), and the incidence of head and neck cancer (HNC) in Greater Manchester and East Cheshire. Understanding this relationship can help inform targeted public health interventions and reduce healthcare disparities. Methods Using Multidisciplinary Team (MDT) lists, 236 HNC patients from Manchester University NHS Foundation Trust were identified. Patient demographics and residential postcodes were extracted from the HIVE electronic patient record system. Postcodes were then mapped to IMD deciles using the UK Government's official postcode-to-IMD lookup tool. This allowed for the categorisation of patients by area-level socioeconomic deprivation. Results The analysis revealed a negative correlation (ρ = -0.21) between socioeconomic status, as indicated by IMD decile, and the incidence of HNC cases. Statistical analysis showed that this correlation was not statistically significant at the α = 0.05 level. Conclusion While this study did not identify a statistically significant correlation between socioeconomic deprivation and HNC incidence, a weak negative trend was observed. These exploratory findings suggest potential geographic and socioeconomic patterns that warrant further investigation. Understanding these trends may support more targeted public health strategies - especially in regions with a higher disease burden - and contribute to efforts aimed at earlier diagnosis and improved health outcomes.
Citation
Chotai N, Yadav M, K Amarasena D, Kumar R. Cancer Clusters: Geographic Disparities in Head and Neck Cancer Incidence in Greater Manchester and East Cheshire. Cureus. 2025 Jul 14;17(7):e87936. doi: 10.7759/cureus.87936
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Article