ERS/ATS technical standard on interpretive strategies for routine lung function tests

dc.contributor.authorStanojevic, Sanja
dc.contributor.authorKaminsky, David A
dc.contributor.authorMiller, Martin R
dc.contributor.authorThompson, Bruce
dc.contributor.authorAliverti, Andrea
dc.contributor.authorBarjaktarevic, Igor
dc.contributor.authorCooper, Brendan G
dc.contributor.authorCulver, Bruce
dc.contributor.authorDerom, Eric
dc.contributor.authorHall, Graham L
dc.contributor.authorHallstrand, Teal S
dc.contributor.authorLeuppi, Joerg D
dc.contributor.authorMacIntyre, Neil
dc.contributor.authorMcCormack, Meredith
dc.contributor.authorRosenfeld, Margaret
dc.contributor.authorSwenson, Erik R
dc.contributor.departmentOutpatient Departmenten_US
dc.contributor.roleHealthcare Scientistsen_US
dc.contributor.trustauthorCooper, Brendan G
dc.date.accessioned2023-08-15T13:19:22Z
dc.date.available2023-08-15T13:19:22Z
dc.date.issued2022-07-13
dc.description.abstractBackground: Appropriate interpretation of pulmonary function tests (PFTs) involves the classification of observed values as within/outside the normal range based on a reference population of healthy individuals, integrating knowledge of physiological determinants of test results into functional classifications and integrating patterns with other clinical data to estimate prognosis. In 2005, the American Thoracic Society (ATS) and European Respiratory Society (ERS) jointly adopted technical standards for the interpretation of PFTs. We aimed to update the 2005 recommendations and incorporate evidence from recent literature to establish new standards for PFT interpretation. Methods: This technical standards document was developed by an international joint Task Force, appointed by the ERS/ATS with multidisciplinary expertise in conducting and interpreting PFTs and developing international standards. A comprehensive literature review was conducted and published evidence was reviewed. Results: Recommendations for the choice of reference equations and limits of normal of the healthy population to identify individuals with unusually low or high results are discussed. Interpretation strategies for bronchodilator responsiveness testing, limits of natural changes over time and severity are also updated. Interpretation of measurements made by spirometry, lung volumes and gas transfer are described as they relate to underlying pathophysiology with updated classification protocols of common impairments. Conclusions: Interpretation of PFTs must be complemented with clinical expertise and consideration of the inherent biological variability of the test and the uncertainty of the test result to ensure appropriate interpretation of an individual's lung function measurements.en_US
dc.identifier.citationStanojevic S, Kaminsky DA, Miller MR, Thompson B, Aliverti A, Barjaktarevic I, Cooper BG, Culver B, Derom E, Hall GL, Hallstrand TS, Leuppi JD, MacIntyre N, McCormack M, Rosenfeld M, Swenson ER. ERS/ATS technical standard on interpretive strategies for routine lung function tests. Eur Respir J. 2022 Jul 13;60(1):2101499. doi: 10.1183/13993003.01499-2021en_US
dc.identifier.doi10.1183/13993003.01499-2021
dc.identifier.eissn1399-3003
dc.identifier.issn0903-1936
dc.identifier.pmid34949706
dc.identifier.urihttp://hdl.handle.net/20.500.14200/1691
dc.language.isoenen_US
dc.publisherEuropean Respiratory Societyen_US
dc.relation.urlhttps://erj.ersjournals.com/en_US
dc.rightsThe content of this work is not subject to copyright. Design and branding are copyright ©ERS 2022. For reproduction rights and permissions contact permissions@ersnet.org.
dc.source.journaltitleEuropean Respiratory Journal
dc.subjectPublic health. Health statistics. Occupational health. Health educationen_US
dc.subjectMicrobiology. Immunologyen_US
dc.subjectPaediatricsen_US
dc.subjectHuman physiologyen_US
dc.titleERS/ATS technical standard on interpretive strategies for routine lung function testsen_US
dc.typeArticle
dspace.entity.typePublication
oa.grant.openaccessnaen_US
rioxxterms.versionNAen_US
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