Cardiovascular manifestations in idiopathic inflammatory myopathies
Shah, Meera Shinjo, Samuel Katsuyuki Day, Jessica
Shah, Meera
Shinjo, Samuel Katsuyuki
Day, Jessica
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Affiliation
Indraprastha Apollo Hospital; Universidade de São Paulo; Royal Melbourne Hospital; Sandwell and West Birmingham NHS Trust; et al.
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Publication date
2023-05-06
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Abstract
Cardiovascular involvement in idiopathic inflammatory myopathies (IIM) is an understudied area which is gaining increasing recognition in recent times. Recent advances in imaging modalities and biomarkers have allowed the detection of subclinical cardiovascular manifestations in IIM. However, despite the availability of these tools, the diagnostic challenges and underestimated prevalence of cardiovascular involvement in these patients remain significant. Notably, cardiovascular involvement remains one of the leading causes of mortality in patients with IIM. In this narrative literature review, we outline the prevalence and characteristics of cardiovascular involvement in IIM. Additionally, we explore investigational modalities for early detection of cardiovascular involvement, as well as newer approaches in screening to facilitate timely management. Key points • Cardiac involvement in IIM in majority cases is subclinical and a major cause of mortality. • Cardiac magnetic resonance imaging is sensitive for detection of subclinical cardiac involvement.
Citation
Shah M, Shinjo SK, Day J, Gupta L. Cardiovascular manifestations in idiopathic inflammatory myopathies. Clin Rheumatol. 2023 Oct;42(10):2557-2575. doi: 10.1007/s10067-023-06599-4
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Article