Laryngeal leishmaniasis in a patient taking inhaled corticosteroids
Roberts, Rachel Margaret ; ; Phillips, David
Roberts, Rachel Margaret
Phillips, David
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Affiliation
Queen Elizabeth Hospital Birmingham; South Warwickshire University NHS Foundation Trust
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Publication date
2016-06-21
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Abstract
We present a case of a man in his late 60s, who had spent 3-4 months of the year in rural Spain, presenting with intermittent hoarseness of voice. He had a background of asthma and bronchiectasis, and was taking inhaled corticosteroids. His dysphonia was initially managed as bronchiectasis with little improvement. Bronchoscopy revealed a cystic lesion on his left vocal fold, and tissue biopsy revealed Leishmania amastigotes. This confirmed a diagnosis of laryngeal leishmaniasis. We propose that this is likely secondary to his inhaled corticosteroid therapy. The infection was treated with a 30-day course of miltefosine, and at most recent follow-up the patient was deemed free from leishmanial infection.
Citation
Roberts RM, Mukherjee J, Phillips D. Laryngeal leishmaniasis in a patient taking inhaled corticosteroids. BMJ Case Rep. 2016 Jun 21;2016:bcr2016215444. doi: 10.1136/bcr-2016-215444.
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Article