Filling the Gap - Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient: A European Consensus View
Wehling, M. Ashton, C. Ekpo, E. Gwynn, S. Laville, M. Olsson, K. Spring, M.
Wehling, M.
Ashton, C.
Ekpo, E.
Gwynn, S.
Laville, M.
Olsson, K.
Spring, M.
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Affiliation
Center for Geriatric Pharmacology in Mannheim; South Warwickshire University NHS Foundation Trust; Lewisham and Greenwich NHS Trust; SG Market Access Ltd, Chichester; Lyon Sud University Hospital, Pierre Benite, France; Lund University, Sweden; Kingston and Richmond NHS Foundation Trust
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Publication date
2016-10-04
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Abstract
Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group.
Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general practitioners and other doctors to test agreement at the European level.
Results: 64 responses were evaluated from around Europe. Agreement was achieved in 86% of the statements following amendment and redistribution of 6 of the statements. The survey and its feedback prompted the development of 13 recommendations related to the diagnosis and treatment of hyponatraemia including SIADH.
Conclusion: The series of 13 recommendations developed here is intended to increase clarity for clinicians managing older patients with hyponatraemia and SIADH. Surprisingly, despite the lack of clear guidelines or recommendations for this age group consensus levels for the author-based statements were high among the respondents.
Citation
Wehling M, Ashton C, Ekpo E, Gwynn S, Laville M, Olsson K, Spring M. Filling the Gap - Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient: A European Consensus View. Drug Res (Stuttg). 2017 Jan;67(1):5-12. doi: 10.1055/s-0042-115015. Epub 2016 Oct 4.
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Article