Recurrent severe respiratory infections with low CRP secondary to autoimmune IL-6 deficiency.
Hackney, Alexander James, Sunil Karanam, Surendra
Hackney, Alexander
James, Sunil
Karanam, Surendra
Citations
Altmetric:
Affiliation
Sandwell and West Birmingham NHS Trust;
Other Contributors
Publication date
2021-06-21
Subject
Collections
Research Projects
Organizational Units
Journal Issue
Abstract
C reactive protein (CRP) is an inflammatory protein that is often used in conjunction with the clinical presentation of a patient to help with quantifying infection severity and measuring treatment response. We report the case of a patient who presented with severe pneumonias but had a suboptimal CRP response, later diagnosed as having an underlying immunodeficiency. This case exemplifies the need to consider immunodeficiency as an underlying pathophysiological cause in patients presenting with complicated and severe infections.
Citation
Hackney A, James S, Karanam S. Recurrent severe respiratory infections with low CRP secondary to autoimmune IL-6 deficiency. BMJ Case Rep. 2021 Jun 21;14(6):e243334. doi: 10.1136/bcr-2021-243334.
Type
Article
Other
Other