Building ADMISSION - a research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital
Witham, Miles D Bartle, Victoria Bellass, Sue Bunn, Jonathan G Cartner, Duncan Cordell, Heather J Doal, Rominique Evison, Felicity Gallier, Suzy Harris, Steve
Witham, Miles D
Bartle, Victoria
Bellass, Sue
Bunn, Jonathan G
Cartner, Duncan
Cordell, Heather J
Doal, Rominique
Evison, Felicity
Gallier, Suzy
Harris, Steve
Affiliation
Newcastle University; Newcastle Upon Tyne Hospitals NHS Foundation Trust; ADMISSION Research Collaborative; Manchester Metropolitan University; University College London Hospitals NHS Foundation Trust; University of Birmingham; University Hospitals Birmingham NHS Foundation Trust; University College London; University of Dundee
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Publication date
2025-02-01
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Abstract
Background: Multiple long-term conditions (MLTCs; commonly referred to as multimorbidity) are highly prevalent among people admitted to hospital and are therefore of critical importance to hospital-based healthcare systems. To date, most research on MLTCs has been conducted in primary care or the general population with comparatively little work undertaken in the hospital setting.
Purpose: To describe the rationale and content of ADMISSION: a four-year UK Research and Innovation and National Institute of Health and Care Research funded interdisciplinary programme that seeks, in partnership with public contributors, to transform care for people living with MLTCs admitted to hospital.
Research design: Based across five UK academic centres, ADMISSION combines expertise in clinical medicine, epidemiology, informatics, computing, biostatistics, social science, genetics and care pathway mapping to examine patterns of conditions, mechanisms, consequences and pathways of care for people with MLTCs admitted to hospital.
Data collection: The programme uses routinely collected electronic health record data from large UK teaching hospitals, population-based cohort data from UK Biobank and routinely collected blood samples from The Scottish Health Research Register and Biobank (SHARE). These approaches are complemented by focused qualitative work exploring the perspectives of healthcare professionals and the lived experience of people with MLTCs admitted to hospital.
Conclusion: ADMISSION will provide the necessary foundations to develop novel ways to prevent and treat MLTCs and their consequences in people admitted to hospital and to improve care systems and the quality of care for this underserved group.
Citation
Witham MD, Bartle V, Bellass S, Bunn JG, Cartner D, Cordell HJ, Doal R, Evison F, Gallier S, Harris S, Hillman SJ, Holding R, Leroux P, Marshall T, Matthews FE, Missier P, Nair A, Osman M, Pearson ER, Plummer C, Pretorius S, Richardson SJ, Robinson SM, Sapey E, Scharf T, Shah R, Shahmandi M, Singer M, Suklan J, Wason JM, Cooper R, Sayer AA. Building ADMISSION - A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital. J Multimorb Comorb. 2025 Feb 1;15:26335565251317940. doi: 10.1177/26335565251317940.
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Article