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Guideline for the management of conception and pregnancy in thalassaemia syndromes : a British Society for Haematology guideline

Shah, Farrukh T
Nicolle, Sarah
Garg, Mamta
Lieberman, Gidon
Anthony, Karen
Mensah, Amma Kyei
Nicolle, Sarah
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Whittington Health; University Hospitals Coventry and Warwickshire; Leicester Royal infirmary; Sandwell and West Birmingham NHS Trust
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2024-05-07
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Abstract
This comprehensive guideline, developed by a representative group of UK-based medical experts specialising in haemoglobinopathies, addresses the management of conception and pregnancy in patients with thalassaemia. A systematic search of PubMed and EMBASE using specific keywords, formed the basis of the literature review. Key terms included "thalassaemia," "pregnancy," "Cooley's anaemia," "Mediterranean anaemia," and others, covering aspects such as fertility, iron burden and ultrasonography. The guideline underwent rigorous review by prominent organisations, including the Endocrine Society, the Royal College of Obstetricians and Gynaecologists (RCOG), the United Kingdom Thalassaemia Society and the British Society of Haematology (BSH) guideline writing group. Additional feedback was solicited from a sounding board of UK haematologists, ensuring a thorough and collaborative approach. The objective of the guideline is to equip healthcare professionals with precise recommendations for managing conception and pregnancy in patients with thalassaemia.
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Shah FT, Nicolle S, Garg M, Pancham S, Lieberman G, Anthony K, Mensah AK. Guideline for the management of conception and pregnancy in thalassaemia syndromes: A British Society for Haematology Guideline. Br J Haematol. 2024 May 7. doi: 10.1111/bjh.19362
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