The use of fibrin glue in pterygium surgery with amniotic membrane transplantation : systematic review and meta-analysis
Karam, Mohammad Alsaif, Abdulmalik Aldubaikhi, Ahmed Aljebreen, Meshaal Alazaz, Rand Almudhaiyan, Tariq AlBaghli, Abdullah
Karam, Mohammad
Alsaif, Abdulmalik
Aldubaikhi, Ahmed
Aljebreen, Meshaal
Alazaz, Rand
Almudhaiyan, Tariq
AlBaghli, Abdullah
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Affiliation
Ibn Sina Hospital; Walsall Healthcare NHS Trust; King Faisal Specialist Hospital and Research Center; Prince Mohammed Bin Abdulaziz Hospital; King Khaled Eye Specialist Hospital; King Abdullah International Medical Research Center; National Guard Hospital
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Publication date
2023-03-09
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Abstract
Four studies enrolling 180 patients were identified. Conjunctival inflammation (odds ratio [OR] 0.21, P = 0.0005) demonstrated a significant difference favoring the fibrin glue group. Despite the trend favoring the use of fibrin glue, there were no significant differences in terms of postoperative pain and discomfort (OR = 0.46, P = 0.25), pterygium recurrence (OR = 0.74, P = 0.48), pyogenic granuloma (OR = 0.47, P = 0.38), and surgical time (mean difference = -17.52, P = 0.13). For secondary outcomes, fibrin glue had significantly fewer cases of graft loss compared with sutures. No statistically significant difference was found in amniotic membrane graft outcomes, time to recurrence, and subconjunctival hemorrhage.
Citation
Karam M, Alsaif A, Aldubaikhi A, Aljebreen M, Alazaz R, Almudhaiyan T, AlBaghli A. The use of fibrin glue in pterygium surgery with amniotic membrane transplantation: Systematic review and meta-analysis. Saudi J Ophthalmol. 2023 Mar 9;37(2):83-89.
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Article