Consensus-based recommendations for optical coherence tomography angiography reporting in uveitis
Pichi, Francesco Carreño, Ester Pavesio, Carlos Denniston, Alastair K Grewal, Dilraj S Deak, Gabor Khairallah, Moncef Ruiz-Cruz, Matilde de Oliveira Dias, Joao Rafael Adan, Alfredo
Pichi, Francesco
Carreño, Ester
Pavesio, Carlos
Denniston, Alastair K
Grewal, Dilraj S
Deak, Gabor
Khairallah, Moncef
Ruiz-Cruz, Matilde
de Oliveira Dias, Joao Rafael
Adan, Alfredo
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2022-02-08
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Abstract
Background/aims: To establish a consensus in the nomenclature for reporting optical coherence tomography angiography (OCTA findings in uveitis.
Methods: The modified Delphi process consisted of two rounds of electronic questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-one items were included for discussion. The three main areas of discussion were: wide field OCTA (WF-OCTA), nomenclature of OCTA findings and OCTA signal attenuation assessment and measurement. Seventeen specialists in uveitis and retinal imaging were selected by the executive committee to constitute the OCTA nomenclature in Uveitis Delphi Study Group. The study endpoint was defined by the degree of consensus for each question: 'strong consensus' was defined as >90% agreement, 'consensus' as 85%-90% and 'near consensus' as >80% but <85%.
Results: There was a strong consensus to apply the term 'wide field' to OCTA images measuring over 70° of field of view, to use the terms 'flow deficit' and 'non-detectable flow signal' to describe abnormal OCTA flow signal secondary to slow flow and to vessels displacement respectively, to use the terms 'loose' and 'dense' to describe the appearance of inflammatory choroidal neovascularisation, and to use the percentage of flow signal decrease to measure OCTA ischaemia with a threshold greater than or equal to 30% as a 'large area'.
Conclusions: This study sets up consensus recommendations for reporting OCTA findings in uveitis by an expert panel, which may prove suitable for use in routine clinical care and clinical trials.
Citation
Pichi F, Carreño E, Pavesio C, Denniston AK, Grewal DS, Deak G, Khairallah M, Ruiz-Cruz M, de Oliveira Dias JR, Adan A, Burke T, Invernizzi A, Schlaen A, Tian M, Agarwal AK, Tucker WR, Sen HN, Lin P, Lim LL, Pepple KL, Munk MR. Consensus-based recommendations for optical coherence tomography angiography reporting in uveitis. Br J Ophthalmol. 2023 Jul;107(7):959-965. doi: 10.1136/bjophthalmol-2021-320021. Epub 2022 Feb 8.
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