Sulfasalazine induced immune thrombocytopenia in a patient with rheumatoid arthritis
Narayan, Nehal Rigby, Shirley Carlucci, Francesco
Narayan, Nehal
Rigby, Shirley
Carlucci, Francesco
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Affiliation
Nuffield Orthopaedic Centre, Oxford; South Warwickshire University NHS Foundation Trust
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Publication date
2016-10-24
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Abstract
Sulfasalazine has long been used for the treatment of rheumatoid arthritis and is often chosen as a first-line treatment. Here, we report a case of sulfasalazine-induced autoimmune thrombocytopenia and review the mechanisms behind drug-induced immune thrombocytopenia (DITP) and the approach to its diagnosis and management.
Keywords: Autoantibodies; Blood platelets disorders; Hematologic diseases; Rheumatic diseases; Rheumatoid arthritis (RA); Thrombocytopenia; Tissues or models.
Citation
Narayan N, Rigby S, Carlucci F. Sulfasalazine induced immune thrombocytopenia in a patient with rheumatoid arthritis. Clin Rheumatol. 2017 Feb;36(2):477-479. doi: 10.1007/s10067-016-3420-9. Epub 2016 Oct 24.
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Article