Physical properties and interaction with the ocular surface of water-gradient contact lenses
Ponzini, Erika Cheloni, Riccardo Zeri, Fabrizio Tavazzi, Silvia
Ponzini, Erika
Cheloni, Riccardo
Zeri, Fabrizio
Tavazzi, Silvia
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Affiliation
University of Milano Bicocca; University of Birmingham; Sandwell and West Birmingham NHS Trust; Aston University
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Publication date
2023-02-22
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Abstract
Since the introduction of silicone hydrogel contact lenses, many silicone-hydrogel materials have been produced, including water-gradient contact lenses with a silicone hydrogel core and a thin hydrogel outer layer (e.g., delefilcon A, verofilcon A, and lehfilcon A). Their properties have been investigated in various studies assessing both the chemical-physical characteristics and the comfort, but the overall picture is not always consistent. In this study, water-gradient technology is reviewed by looking at basic physical properties both in vitro and in vivo and at the interaction with the human ocular surface. Surface and bulk dehydration, surface wetting and dewetting, shear stress, interaction with tear components and with other environmental compounds, and comfort are discussed.
Citation
Ponzini E, Recchioni A, Cheloni R, Zeri F, Tavazzi S. Physical Properties and Interaction With the Ocular Surface of Water-Gradient Contact Lenses. Eye Contact Lens. 2023 Apr 1;49(4):152-159. doi: 10.1097/ICL.0000000000000974
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Article