Vitamin D and physical activity as co-modifiers of muscle health and function - a narrative exploration
Jawed, Inshal Quratul Ain, Hafiza Abdul Razaq, Farah Alam, Farah
Jawed, Inshal
Quratul Ain, Hafiza
Abdul Razaq, Farah
Alam, Farah
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Affiliation
Dow University of Health Sciences; Combined Military Hospital; Civil Hospital; Karachi Medical and Dental College; Walsall Healthcare NHS Trust; Allama Iqbal Medical College; Medicare Hospital; Liaquat University of Medical and Health Sciences; Jinnah Medical & Dental College; Institute of Medical Sciences Lahore; University of Khartoum
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2025-06-25
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Abstract
Bone health requires different factors to grow. One of the main requirements is vitamin D. Much of the regulation of calcium levels also affects muscle strength and function, protein synthesis, and other cellular activities. Furthermore, the benefits of vitamin D on the muscular system are comparable to those of physical activity in terms of shaping the structural and functional changes in muscles. Our paper focuses on the synergistic effects of physical exercise and vitamin D on metabolism how they can impact muscle health, including the physiological rationale, outcomes of its deficiency, and measures for counteraction thereto. Here, we outline the effect of combined interventions for optimizing muscle strength.
Citation
Jawed I, Quratul Ain H, Abdul Razaq F, Qadir MU, Jabeen S, Alam F, Javaid M, Mobin M, Kumar D, Rai R, Abbas SAF, Bin Gulzar AH, Mirza AMW, Alrawa SS, Imam W. Vitamin D and physical activity as co-modifiers of muscle health and function - a narrative exploration. Ann Med Surg (Lond). 2025 Jun 25;87(8):5046-5055. doi: 10.1097/MS9.0000000000003502. PMID: 40787552; PMCID: PMC12333755.
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Article