Alcohol and Heart Failure.
Rasoul D Ajay A Abdullah A Mathew J Lee Wei En B Mashida K Sankaranarayanan R
Rasoul D
Ajay A
Abdullah A
Mathew J
Lee Wei En B
Mashida K
Sankaranarayanan R
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Affiliation
Liverpool University Hospitals NHS Foundation Trust; The Dudley Group NHS Foundation Trust Dudley; University of Liverpool.
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Publication date
26/12/2023
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Abstract
Alcohol is the most frequently consumed toxic substance in the world and remains a major global public health issue, with one in three adults consuming it worldwide. Alcohol use is a leading risk factor for disease, contributing to over 60 acute and chronic health conditions, with a particularly complex association with cardiovascular disease. Chronic excessive alcohol consumption is associated with a range of cardiac complications, including decreased myocardial contractility, hypertension, arrhythmias, MI and heart failure. However, low-level alcohol consumption is believed to have a protective effect against ischaemic heart disease and diabetes. In most cohort studies, small to moderate amounts of alcohol consumption have not been linked to heart failure, indicating a threshold effect of alcohol with individual (possibly genetic) predisposition rather than a continuous effect of exposure. This review article explores the potential benefits of alcohol on the heart, the association between alcohol use and alcoholic cardiomyopathy and the epidemiology, clinical correlates and management of alcoholic cardiomyopathy. Competing Interests: Disclosure: The authors have no conflicts of interest to declare. Copyright The Author(s), 2023. Published by Radcliffe Group Ltd.
Citation
Rasoul D, Ajay A, Abdullah A, Mathew J, Lee Wei En B, Mashida K, Sankaranarayanan R. Alcohol and Heart Failure. Eur Cardiol. 2023 Dec 26;18:e65. doi: 10.15420/ecr.2023.12. PMID: 38213665; PMCID: PMC10782426.
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Article