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De novo pancytopaenia in an older adult with severe COVID-19 infection

Lee, Helena
Muneer, Tazeen
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Affiliation
University of Birmingham; Walsall Healthcare NHS Trust; University Hospitals Birmingham NHS Foundation Trust; Sandwell and West Birmingham Hospitals NHS Trust;
Sandwell and West Birmingham NHS Trust
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Publication date
2022-11
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Abstract
During the COVID-19 pandemic, it was recognised that SARS-CoV-2 can cause multisystem illness. Non-respiratory complications observed early in the pandemic were haematological in nature. A rare but serious haematological complication of COVID-19 infection is pancytopaenia. We describe a case of an older adult without pre-existing haematological disease or risk factors for cell dyscrasia with severe pancytopaenia induced by COVID-19, who developed critical illness requiring respiratory support in intensive care and died. Our case report highlights that de novo pancytopaenia may only present with mild dermatological manifestations and may indicate severe COVID-19 infection. Management is primarily supportive and early involvement of haematology should be sought.
Citation
Lee H, Thein OS, Muneer T. De novo pancytopaenia in an older adult with severe COVID-19 infection. BMJ Case Rep. 2022 Nov 15;15(11):e252609.
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Article
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