British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for 1/2 variants in ovarian cancer in the United Kingdom.
Manchanda, Ranjit Gourley, Charlie George, Angela Wallace, Andrew Williams, Sarah Wallis, Yvonne Edmondson, Richard Nicum, Shibani
Manchanda, Ranjit
Gourley, Charlie
George, Angela
Wallace, Andrew
Williams, Sarah
Wallis, Yvonne
Edmondson, Richard
Nicum, Shibani
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Affiliation
University of Birmingham; Barts Health NHS Trust; Royal Marsden Hospital NHS Trust; Sandwell and West Birmingham NHS Trust
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Publication date
2021-01-19
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Abstract
The British Gynecological Cancer Society and the British Association of Gynecological Pathologists established a multidisciplinary consensus group comprising experts in surgical gynecological oncology, medical oncology, genetics, and laboratory science, and clinical nurse specialists to identify the optimal pathways to BRCA germline and tumor testing in patients with ovarian cancer in routine clinical practice. In particular, the group explored models of consent, quality standards identified at pathology laboratories, and experience and data from pioneering cancer centers. The group liaised with representatives from ovarian cancer charities to also identify patient perspectives that would be important to implementation. Recommendations from these consensus group deliberations are presented in this manuscript.
Citation
Sundar S, Manchanda R, Gourley C, George A, Wallace A, Balega J, Williams S, Wallis Y, Edmondson R, Nicum S, Frost J, Attygalle A, Fotopoulou C, Bowen R, Bell D, Gajjar K, Ramsay B, Wood NJ, Ghaem-Maghami S, Miles T, Ganesan R. British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for BRCA1/2 variants in ovarian cancer in the United Kingdom. Int J Gynecol Cancer. 2021 Feb;31(2):272-278. doi: 10.1136/ijgc-2020-002112. Epub 2021 Jan 19. Erratum in: Int J Gynecol Cancer. 2021 Dec;31(12):1619.
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