Apparent diffusion coefficient (ADC): A potential in vivo biological surrogate of the incidentally discovered bone lesions at 3T MRI.
Nouh, M R Doweidar, Ahmed Khalil, Abdullah Mohie-Eddin
Nouh, M R
Doweidar, Ahmed
Khalil, Abdullah Mohie-Eddin
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Alexandria University; El-Razi Hospital; Sandwell and West Birmingham NHS Trust
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Publication date
2021-11-25
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Abstract
The mean ADC value (mean±SD) of all malignant tumors (including cartilaginous neoplasms) was [0.92 ± 0.40] × 10-3 mm2/s. This significantly differed from those of both primary benign tumors [1.14 ± 0.24] × 10-3 mm2/s, (p = 0.011), and all non-malignant lesions collectively [1.29 ± 0.44] × 10-3 mm2/s, (p < 0.001). Using mADC value of ≤ 1.1 × 10-3 mm2/s resulted in 86.1% sensitivity and 62.5% specificity for characterizing a lesion as a malignant. The inter-rater reliability was almost perfect (95% CI = 0.954-0.985).
Citation
Nouh, M. R., Doweidar, A., & Khalil, A. M. (2021). Apparent diffusion coefficient (ADC): A potential in vivo biological surrogate of the incidentally discovered bone lesions at 3T MRI. European journal of radiology open, 8, 100386.
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Article