Ethnic differences in the rates of posterior capsule rupture and long-term sequelae in phacoemulsification Cataract surgery
Mohite, Abhijit A Panthagani, Jesse Sharif, Walid Feinberg, Leo Shah, Peter Masood, Imran
Mohite, Abhijit A
Panthagani, Jesse
Sharif, Walid
Feinberg, Leo
Shah, Peter
Masood, Imran
Citations
Altmetric:
Affiliation
Royal Wolverhampton Hospitals NHS Trust; Sandwell and West Birmingham NHS Trust; University Hospitals Birmingham NHS Foundation Trust; University College London; University of Wolverhampton
Other Contributors
Publication date
2024-02-29
Subject
Collections
Research Projects
Organizational Units
Journal Issue
Abstract
Purpose The purpose of this study is to investigate the rates of posterior capsular rupture (PCR) and its sequelae during phacoemulsification across different ethnicities. Methods This is a retrospective cohort study of all consecutive phacoemulsification cases complicated by PCR that met the inclusion criteria over a four-year period at a single tertiary eye centre in the United Kingdom (UK). Results PCR occurred in 0.85% of cases overall (157/18,481). PCR rates were 1.8% (26/1485), 1.2% (51/4350), and 0.7% (75/10,927) in African-Caribbean, Indian subcontinent, and Caucasian patients, respectively (p < 0.001). Mean final corrected distance visual acuity improved (p < 0.05) in all ethnic groups (0.40 ± 0.57 logMAR) compared to pre-op (0.78 ± 0.61 logMAR). Post-operative cystoid macular oedema and unstable intraocular pressure rates following PCR did not statistically differ amongst ethnicities (p = 0.37 and p = 0.75, respectively). However, post-operative uveitis rates significantly differed at 11.5%, 15.7%, and 1.3% amongst the three ethnic groups, respectively (p = 0.01). Conclusion This is the first study to highlight a possible link between patient ethnicity and the risk of PCR during phacoemulsification cataract surgery. We observed significantly greater numbers of PCR cases amongst certain ethnic groups (highest in African-Caribbean eyes, then Indian subcontinental eyes, and lowest in Caucasian eyes) within the same multi-cultural urban population. Ethnicity may therefore be a contributing factor for PCR and should potentially be taken into consideration during preoperative risk stratification.
Citation
Mohite AA, Panthagani J, Sharif W, Feinberg L, Shah P, Masood I. Ethnic Differences in the Rates of Posterior Capsule Rupture and Long-Term Sequelae in Phacoemulsification Cataract Surgery. Cureus. 2024 Feb 29;16(2):e55270. doi: 10.7759/cureus.55270
Type
Article