Comparison of omental patch closure versus simple closure for laparoscopic repair of perforated peptic ulcer : a systematic review and meta-analysis
Mohamedahmed, Ali Yasen Y Albendary, Mohamed Patel, Kamlesh Ayeni, Adewale Adeoba Zaman, Shafquat Zaman, Osama Ibrahim, Rashid Mobarak, Dham
Mohamedahmed, Ali Yasen Y
Albendary, Mohamed
Patel, Kamlesh
Ayeni, Adewale Adeoba
Zaman, Shafquat
Zaman, Osama
Ibrahim, Rashid
Mobarak, Dham
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Sandwell and West Birmingham NHS Trust; Russells Hall Hospital; University Hospitals Plymouth NHS Trust
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Publication date
2022-03-25
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Abstract
Aims: To evaluate comparative outcomes of laparoscopic repair of perforated peptic ulcer with omental patch versus without omental patch. Methods: A systematic search of multiple electronic data sources was conducted, and all studies comparing laparoscopic repair of perforated peptic ulcer (PPU) with and without omental patch were included. Operative time, postoperative complications, re-operation and mortality were the evaluated outcome parameters for the meta-analysis. Revman 5.3 was used for data analysis. Results: Four observational studies reporting a total number of 438 patients who underwent laparoscopic repair of PPU with (n = 268) or without (n = 170) omental patch were included. Operative time was significantly shorter in no-omental patch group (NOP) when compared to omental patch group (P = .02). There was no significant difference in the risk of postoperative ileus (Odd ratio (OR) .76, P = .61), leakage (OR 1.17, P = .80), wound infection (OR 1.89, P = .34), intra-abdominal abscess (OR 1.17, P = .87), re-operation (OR .00, P = .94) and mortality (OR .55, P = .48). Moreover, length of hospital stay was comparable between the two groups (P = .81). Conclusion: Laparoscopic repair of PPU with or without omental patch have comparable postoperative complications and mortality rate. However, considering the shorter operative time, no-omental patch approach is an attractive and more favourable choice. Well-designed randomized controlled trials are needed to investigate this comparison.
Citation
Mohamedahmed AYY, Albendary M, Patel K, Ayeni AA, Zaman S, Zaman O, Ibrahim R, Mobarak D. Comparison of Omental Patch Closure Versus Simple Closure for Laparoscopic Repair of Perforated Peptic Ulcer: A Systematic Review and Meta-Analysis. Am Surg. 2023 May;89(5):2005-2013. doi: 10.1177/00031348211067991
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Article