Paediatric mitral valve disease - from presentation to management
Iddawela, Sashini Joseph, Prince Josiah Sajanthan Ganeshan, Roshan Shah, Hussain Imtiaz Olatigbe, Temitope Adebowale Temidayo Anyu, Anawinla Ta Hadi, Khaled Tarmahomed, Abdulla Harky, Amer
Iddawela, Sashini
Joseph, Prince Josiah Sajanthan
Ganeshan, Roshan
Shah, Hussain Imtiaz
Olatigbe, Temitope Adebowale Temidayo
Anyu, Anawinla Ta
Hadi, Khaled
Tarmahomed, Abdulla
Harky, Amer
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Affiliation
University Hospitals Birmingham; University of Liverpool; University College London; Medical University-Sofia; King's College London; Alder Hey Children Hospital; Liverpool Heart and Chest Hospital
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Publication date
2021-07-26
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Abstract
Mitral valve diseases are relatively rare in the paediatric population; however, they can cause considerable mortality and morbidity worldwide. Acquired causes are a major contributor to cardiovascular disease burden in the paediatric population. Diseases can be detected before birth, at birth, or when the child is older and presents with symptoms of advanced heart failure. Definitive management consists of surgical intervention, with mitral valve replacement being the gold standard.Conclusion: Repair has been gaining popularity; however, its outcomes require further study. Percutaneous mitral balloon valvuloplasty is an emerging technique which holds promise as a bridge to surgical treatment. The effect of these interventions on quality of life must be emphasised and requires further study. What is Known: • The epidemiology of mitral valve disease in the paediatric population - predominant causes include rheumatic disease and congenital defects. • Mitral valve repair and replacement are the standard treatment methods for paediatric mitral valve disease. What is New: • Emergence of percutaneous mitral valve interventions and their potential as bridge-to-surgery or definitive treatment in high-risk surgical candidates. • Recent evidence comparing mitral valve repair and replacement in the paediatric population demonstrates increasing popularity of repair techniques.
Citation
Iddawela S, Joseph PJS, Ganeshan R, Shah HI, Olatigbe TAT, Anyu AT, Hadi K, Tarmahomed A, Harky A. Paediatric mitral valve disease - from presentation to management. Eur J Pediatr. 2022 Jan;181(1):35-44. doi: 10.1007/s00431-021-04208-7. Epub 2021 Jul 26
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Article