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One-step nucleic acid amplification : CK 19 copy number as a predictor of further axillary involvement

Tafazal, Habib
Atherton, Gavin
Amin, Verda
Dakka, Mahmoud
Park, Michael
Smith, Adrian
Harries, Simon
Jones, Lucie
Clarke, Dayalan
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South Warwickshire University NHS Foundation Trust
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Publication date
2015-06
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Abstract
Introduction: In 2013, the National Institute of Clinical Excellence (NICE) endorsed the use of One step nucleic acid amplification (OSNA) in clinical practice. Our study aims to seek a correlation between the OSNA results, indicated by CK 19 mRNA copy numbers and the likelihood of non-sentinel axillary involvement in patients with macro-metastases.
Citation
Tafazal H, Atherton G, Amin V, Dakka M, Park M, Smith A, Harries S, Jones L, Clarke D. P098. One-step nucleic acid amplification: CK 19 copy number as a predictor of further axillary involvement. Eur J Surg Oncol. 2015 Jun;41(6):S54. doi: 10.1016/j.ejso.2015.03.136.
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