Cerebral hemodynamics at altitude: effects of hyperventilation and acclimatization on cerebral blood flow and oxygenation.
Sanborn, Matthew R ; Edsell, Mark E ; Kim, Meeri N ; Mesquita, Rickson ; Putt, Mary E ; Yow, Heng ; Wilson, Mark H ; Yodh, Arjun G ; Grocott, Mike ; Martin, Daniel S ... show 1 more
Sanborn, Matthew R
Edsell, Mark E
Kim, Meeri N
Mesquita, Rickson
Putt, Mary E
Yow, Heng
Wilson, Mark H
Yodh, Arjun G
Grocott, Mike
Martin, Daniel S
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2015-03-18
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Abstract
Objective: Alterations in cerebral blood flow (CBF) and cerebral oxygenation are implicated in altitude-associated diseases. We assessed the dynamic changes in CBF and peripheral and cerebral oxygenation engendered by ascent to altitude with partial acclimatization and hyperventilation using a combination of near-infrared spectroscopy, transcranial Doppler ultrasound, and diffuse correlation spectroscopy.
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Wilderness Environ Med . 2015 Jun;26(2):133-41
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Article