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Cerebral hemodynamics at altitude: effects of hyperventilation and acclimatization on cerebral blood flow and oxygenation.

Sanborn, Matthew R
Edsell, Mark E
Kim, Meeri N
Mesquita, Rickson
Putt, Mary E
Yow, Heng
Wilson, Mark H
Yodh, Arjun G
Grocott, Mike
Martin, Daniel S
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2015-03-18
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Objective: Alterations in cerebral blood flow (CBF) and cerebral oxygenation are implicated in altitude-associated diseases. We assessed the dynamic changes in CBF and peripheral and cerebral oxygenation engendered by ascent to altitude with partial acclimatization and hyperventilation using a combination of near-infrared spectroscopy, transcranial Doppler ultrasound, and diffuse correlation spectroscopy.
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Wilderness Environ Med . 2015 Jun;26(2):133-41
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