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Widening access to penicillin allergy assessment in the United Kingdom-a proposed implementation plan for the National Health Service (NHS).

Porter, Catherine E
Roleston, Caity
Bethune, Claire
Boards, Jenny
Brown, Colin S
Clarke, Ian
Fielding, Joanne
Howard, Philip
Jamieson, Conor
Misbah, Siraj A
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2026-01-07
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Abstract
Globally, there is increasing evidence that incorrect penicillin allergy labels negatively affect patient outcomes, antibiotic prescribing and antimicrobial resistance, leading to growing concern about this patient safety issue and how to resolve it. While many millions of patients worldwide have incorrect penicillin allergy labels, there are too few specialist allergists and a lack of 'point-of-care' tests to address this problem. Numerous research studies now provide evidence of the feasibility and importance of widening access to penicillin allergy assessment. Researchers from two UK-based studies (SPACE and ALABAMA), in collaboration with key stakeholders including patient representatives, gave their views to shape a high-level implementation plan to facilitate widening access to penicillin allergy assessment in the UK. This Viewpoint describes the basis of the implementation plan and summarizes the key actions required for successful delivery. While the plan is intended for the UK, we hope to promote international shared learning and collaboration to address this global problem informed by the UK context.
Citation
Porter CE, Roleston C, Bethune C, Boards J, Brown CS, Clarke I, Fielding J, Howard P, Jamieson C, Misbah SA, Moss AC, Pavitt SH, Powell N, Savic L, Savic S, Krishna MT, Tonkin-Crine S, Williams I, A T Sandoe J. Widening access to penicillin allergy assessment in the United Kingdom-a proposed implementation plan for the National Health Service (NHS). JAC Antimicrob Resist. 2026 Jan 7;8(1):dlaf240. doi: 10.1093/jacamr/dlaf240.
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