Creating a health utility value for birdshot chorioretinopathy.
Sekaran, Anisha Shamdas, Mohith Barry, Robert J Denniston, Alastair K Murray, Philip I
Sekaran, Anisha
Shamdas, Mohith
Barry, Robert J
Denniston, Alastair K
Murray, Philip I
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2020-09-18
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Abstract
Purpose: To create a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) utilities.
Method: Adult BCR patients completed TTO, SG, EQ-5D-5L, and NEI VFQ-25 questionnaires and underwent a detailed history and clinical examination.
Results: A total of 28 BCR patients (9 M, 19 F; mean age 62 years, range 47-83) were included. There were 22 patients with a logMAR vision of 0.3 or better in both eyes. Mean TTO was 0.90 ± SD 0.18 (range 0.33-1.0) and mean SG was 0.94 ± SD 0.14 (range 0.5-1.0). TTO correlated with EQ-5D-5L index value (p = .024) and NEI VFQ-25 composite score (p = .015).
Conclusions: Of 28 patients with BCR, 11 would trade remaining life (mean 5.4 years), and 6 would take a risk of immediate death (mean 28% risk), in return for perfect vision in both eyes for the rest of their life.
Citation
Sekaran A, Shamdas M, Barry RJ, Denniston AK, Murray PI. Creating a Health Utility Value for Birdshot Chorioretinopathy. Ocul Immunol Inflamm. 2022 Jan 2;30(1):73-80. doi: 10.1080/09273948.2020.1799034. Epub 2020 Sep 18
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