Comparison of staged repair versus single-stage complete repair for pulmonary atresia with ventricular septal defect: A systematic review and meta-analysis.
Elhedai, Huzeifa Mohamed, Mustafa Mohammed, Salma Saeed S Mustafa, Khalid H H Seedahmed, Mohamed Hassan A
Elhedai, Huzeifa
Mohamed, Mustafa
Mohammed, Salma Saeed S
Mustafa, Khalid H H
Seedahmed, Mohamed Hassan A
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Affiliation
Birmingham Women's and Children's NHS Foundation Trust; North Middlesex University Hospital NHS Trust; University Hospitals Birmingham NHS Foundation Trust; Sandwell and West Birmingham NHS Trust; et al.
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Publication date
2021-11-18
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Abstract
Four comparative studies reporting a total of 264 patients who underwent SR (167 patients) or CR (97 patients) were included. Total mortality was higher in the SR group compared to the CR group (odds ratio (OR) 2.58, P = 0.03). Two groups were comparable regarding operative and early post-operative mortality (OR 1.37, P = 0.62), post-operative ventilation duration (mean difference (MD) - 1.58, P = 0.43), need for post-operative ECMO support rate (OR 4.72, P = 0.16), transcatheter re-intervention rate (OR 0.60, P = 0.53), unplanned re-operation rate (OR 0.73, P = 0.57), and LOS (MD - 3.39, P = 0.45). Higher rate of freedom from RVOT re-intervention was observed in the SR group (OR 4.16, P = 0.00001).
Citation
lhedai H, Mohamed M, Mohammed SSS, Mustafa KHH, Seedahmed MHA, Mohamedahmed AYY. Comparison of staged repair versus single-stage complete repair for pulmonary atresia with ventricular septal defect: A systematic review and meta-analysis. Indian J Thorac Cardiovasc Surg. 2022 Jan;38(1):5-16. doi: 10.1007/s12055-021-01296-w.
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Article