Acute Coronary Syndrome Associated with Calcified Coronary Lesions
Sharma, Vinoda
Sharma, Vinoda
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Affiliation
Sandwell and West Birmingham NHS Trust
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Publication date
2021-03
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Abstract
A large majority of acute coronary syndromes are triggered by plaque rupture, plaque erosion and a small number of cases resulting from a calcified nodule. The calcified nodule is defined as an eruptive accumulation of a nodular calcification within the coronary artery. Between 2% and 7% of life-threatening acute coronary thrombosis is provoked by calcified nodules. Coronary calcification cannot be assessed on coronary angiography alone and hence adjunctive intracoronary imaging devices are advocated to evaluate the severity and characterisation of the plaque morphology. Heavily calcified coronary lesions are incredibly difficult to dilate optimally by employing the conventional balloons and are usually associated with peri - procedural complications, stent under - expansion, delamination of drugs and polymers from stents, mal-apposition, and unfavourable clinical outcomes. Adequate calcium modification is pivotal to mandate better procedural success, and to enable optimal stent expansion and apposition, which subsequently may result in better long - term outcomes. We analyse the literature in a cohort of patients with calcified coronary lesions presenting with acute coronary syndrome along with the description of the various current calcium - modification techniques
Citation
Sheikh AS, Connolly DL, Sharma V. Acute Coronary Syndrome Associated with Calcified Coronary Lesions. Int J Cardiovasc Dis Diagn. 2021 Mar 23;6(1): 025-033
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Article