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Beyond gastroenteritis : a case of Salmonella infection leading to adrenal insufficiency
Wint Htal, Thwe Thwe Tin Hla, Aye Pyae Paing, Aye Moh Moh Thura, Kyaw Pollard, Clare
Wint Htal, Thwe Thwe
Tin Hla, Aye Pyae
Paing, Aye Moh Moh
Thura, Kyaw
Pollard, Clare
Affiliation
Glan Clwyd Hospital, Bodelwyddan; Victoria Hospital Kirkcaldy; West Middlesex University Hospital; South Warwickshire University NHS Foundation Trust
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Publication date
2025-10-13
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Abstract
Primary adrenal insufficiency (PAI), or Addison's disease, is a rare and potentially life-threatening condition that requires prompt diagnosis and management. While most cases are autoimmune, other causes include infections such as Salmonella, though this is rarely reported. We describe a case of bilateral adrenal abscesses and adrenal insufficiency secondary to disseminated Salmonella Saintpaul infection in a previously healthy 20-year-old male following travel to Thailand. This case highlights the importance of early recognition of adrenal involvement in septic patients with persistent fever and electrolyte imbalances, even in immunocompetent individuals.
Citation
Wint Htal TT, Tin Hla AP, Paing AMM, Thura K, Pollard C. Beyond Gastroenteritis: A Case of Salmonella Infection Leading to Adrenal Insufficiency. Cureus. 2025 Oct 13;17(10):e94443. doi: 10.7759/cureus.94443.
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© Copyright 2025 Wint Htal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.