The Association Between Trajectories of Self-reported Psychotic Experiences and Continuity of Mental Health Care in a Longitudinal Cohort of Adolescents and Young Adults
Gerritsen, Suzanne E Bolhuis, Koen van Bodegom, Larissa S Maras, Athanasios Overbeek, Mathilde M van Amelsvoort, Therese Amj Wolke, Dieter de Girolamo, Giovanni Franić, Tomislav Madan, Jason
Gerritsen, Suzanne E
Bolhuis, Koen
van Bodegom, Larissa S
Maras, Athanasios
Overbeek, Mathilde M
van Amelsvoort, Therese Amj
Wolke, Dieter
de Girolamo, Giovanni
Franić, Tomislav
Madan, Jason
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Affiliation
Erasmus Medical Center; Yulius Mental Health Organization, Dordrecht; ARQ National Psychotrauma Centre, Diemen; Vrije Universiteit Amsterdam; University of Maastricht; Mondriaan Mental Health Care, Heerlen; University of Warwick; IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia; University Hospital Split; University of Split; University College Dublin; Lucena CAMHS, SJOG, Dublin; Coventry and Warwickshire Partnership NHS Trust; Saint Eloi Hospital, Montpellier; University Paris Saclay; Kings College London; South London and Maudsley NHS Foundation Trust; HealthTracker Ltd, Kent; University of Ulm; Department of Neurosciences, KU Leuven
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2024-08
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Abstract
Background and hypothesis: Young people (YP) with psychotic experiences (PE) have an increased risk of developing a psychiatric disorder. Therefore, knowledge on continuity of care from child and adolescent (CAMHS) to adult mental health services (AMHS) in relation to PE is important. Here, we investigated whether the self-reported trajectories of persistent PE were associated with likelihood of transition to AMHS and mental health outcomes.
Study design: In this prospective cohort study, interviews and questionnaires were used to assess PE, mental health, and service use in 763 child and adolescent mental health service users reaching their service's upper age limit in 8 European countries. Trajectories of self-reported PE (3 items) from baseline to 24-month follow-up were determined using growth mixture modeling (GMM). Associations were assessed with auxiliary variables and using mixed models. Study results. At baseline, 56.7% of YP reported PE. GMM identified 5 trajectories over 24 months: medium increasing (5.2%), medium stable (11.7%), medium decreasing (6.5%), high decreasing (4.2%), and low stable (72.4%). PE trajectories were not associated with continuity of specialist care or transition to AMHS. Overall, YP with PE reported more mental health problems at baseline. Persistence of PE or an increase was associated with poorer outcomes at follow-up.
Conclusions: PE are common among CAMHS users when reaching the upper age limit of CAMHS. Persistence or an increase of PE was associated with poorer mental health outcomes, poorer prognosis, and impaired functioning, but were less discriminative for continuity of care.
Citation
Gerritsen SE, Bolhuis K, van Bodegom LS, Maras A, Overbeek MM, van Amelsvoort TAMJ, Wolke D, de Girolamo G, Franić T, Madan J, McNicholas F, Paul M, Purper-Ouakil D, Santosh P, Schulze UME, Singh SP, Street C, Tremmery S, Tuomainen H, Dieleman GC, Mesman E. The Association Between Trajectories of Self-reported Psychotic Experiences and Continuity of Mental Health Care in a Longitudinal Cohort of Adolescents and Young Adults. Schizophr Bull. 2024 Aug 7:sbae136. doi: 10.1093/schbul/sbae136. Epub ahead of print. PMID: 39113641.
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Article