Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study.
Papathanasiou, Athanasios Hibbert, Aimee Tallantyre, Emma Harding, Katharine Selvam, Adithya Panneer Morgan, Matthew Quainton, Charlotte Talaei, Maryam Ingram, Gillian Law, Graham R
Papathanasiou, Athanasios
Hibbert, Aimee
Tallantyre, Emma
Harding, Katharine
Selvam, Adithya Panneer
Morgan, Matthew
Quainton, Charlotte
Talaei, Maryam
Ingram, Gillian
Law, Graham R
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2023-05-20
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Abstract
Background: Annualized relapse rate (ARR) is used as an outcome measure in multiple sclerosis (MS) clinical trials. Previous studies demonstrated that ARR has reduced in placebo groups between 1990 and 2012. This study aimed to estimate real-world ARRs from contemporary MS clinics in the UK, in order to improve the feasibility estimations for clinical trials and facilitate MS service planning.
Citation
Neurol Sci . 2023 Oct;44(10):3629-3635
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Article