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Age-specific Reference Intervals of Abbott Intact PTH-Potential Impacts on Clinical Care.

Kalaria, Tejas
Lawson, Alexander J
Duffy, Joanne
Agravatt, Ashishkumar
Harris, Steve
Ford, Clare
Gama, Rousseau
Webster, Craig
Geberhiwot, Tarekegn
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2024-01-12
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Abstract
PTH increased with age and correlated with age when controlled for 25-hydroxyvitamin D, estimated glomerular filtration rate, and adjusted calcium (r = 0.093, P < .001). The iPTH age-specific reference intervals for 4 age partitions of 18 to 45 years, 46 to 60 years, 61 to 80 years, and 81 to 95 years were 1.6 to 8.6 pmol/L, 1.8 to 9.5 pmol/L, 2.0 to 11.3 pmol/L, and 2.3 to 12.3 pmol/L, respectively. PTH was higher in women compared with men (P < .001). Sex-specific age-related reference intervals could not be derived because of the limited sample size.
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Kalaria T, Lawson AJ, Duffy J, Agravatt A, Harris S, Ford C, Gama R, Webster C, Geberhiwot T. Age-specific Reference Intervals of Abbott Intact PTH-Potential Impacts on Clinical Care. J Endocr Soc. 2024 Jan 12;8(3):bvae004. doi: 10.1210/jendso/bvae004. PMID: 38292595; PMCID: PMC10825829.
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