Neovascular Glaucoma: An Update.
Kalogeropoulos, Dimitrios Sung, Velota Ct Pappa, Chrysavgi Kalogeropoulos, Chris
Kalogeropoulos, Dimitrios
Sung, Velota Ct
Pappa, Chrysavgi
Kalogeropoulos, Chris
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Affiliation
University General Hospital of Ioannina; Sandwell and West Birmingham NHS Trust
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Publication date
2022-11-27
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Abstract
Neovascular glaucoma (NVG) is a severe type of secondary glaucoma with devastating complications and generally poor visual prognosis. NVG is defined by the development of pathological neovessels over the iris and the iridocorneal angle that can block the outflow of aqueous humor, causing elevation of intraocular pressure (IOP). The pathogenesis of NVG is, in most cases, associated with ischemia of the posterior segment, which is most frequently associated with proliferative diabetic retinopathy or central retinal vein occlusion. The advanced stages of NVG are by iris and angle neovascularization, angle, and extremely high IOP, accompanied by ocular pain and poor vision. The therapeutic approach of NVG is based on the reduction of retinal ischemia by panretinal photocoagulation. Intravitreal anti-VEGF administration can contribute to the regression of neovascularization, and topical and systemic medications may be necessary for IOP control. However, if medical treatment with these agents is not enough, surgical procedures may be required to lower IOP and prevent glaucomatous optic neuropathy. Early and prompt diagnosis, with identification of the underlying etiology, can improve IOP control and final visual outcome. The aim of this study is to review current knowledge of the pathogenesis and management of NVG.
Citation
Kalogeropoulos D, Moussa G, Sung VC, Pappa C, Kalogeropoulos C. Neovascular Glaucoma: An Update. Klin Monbl Augenheilkd. 2023 Mar;240(3):305-315. English. doi: 10.1055/a-1956-9348
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Article