Publication

Prevalence of invasive lung cancer in pure ground glass nodules less than 30 mm: A systematic review

AlShammari, Abdullah
Patel, Akshay
Boyle, Mark
Proli, Chiara
Gallesio, Jose Alvarez
Wali, Anuj
De Sousa, Paulo
Lim, Eric
Research Projects
Organizational Units
Journal Issue
Abstract
All published studies were retrospective (n = 28) and the majority conducted in Asia (n = 25). Baseline patient cohorts were mainly from published surgical series (n = 22) or lung cancer screening programs (n = 6). The proportion of minimally invasive and invasive cancer ranged from 0.9 % to 100 % with a pooled prevalence of 42.4 % [95 % CI: 0.28, 0.57]. Considerable heterogeneity was observed (I2 =99 %) and patient selection was the most significant contribution, accounting for 73 % of the observed heterogeneity (p < 0.0001). Meta-regression based on size selection and country of investigation revealed no significant contribution to effect size effect or heterogeneity.
Citation
AlShammari A, Patel A, Boyle M, Proli C, Gallesio JA, Wali A, De Sousa P, Lim E. Prevalence of invasive lung cancer in pure ground glass nodules less than 30 mm: A systematic review. Eur J Cancer. 2024 Dec;213:115116. doi: 10.1016/j.ejca.2024.115116. Epub 2024 Nov 5.
Type
Article
Other
Description
Additional Links
Embedded videos