Development of new antipsychotics: changing trends
Horton, Gemma Maumi, Gurbinder James, Katie Jainer, Ashok Kumar Somashekar, Bettahalasoor
Horton, Gemma
Maumi, Gurbinder
James, Katie
Jainer, Ashok Kumar
Somashekar, Bettahalasoor
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Publication date
2020-08
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Abstract
Introduction: We aimed to examine the changing trends in development of antipsychotics in the past half century.
Materials and Methods: A comprehensive literature search was completed, using MEDLINE, EMBASE and the Cochrane
library.
Findings/conclusion: During the past half century, numerous first-, second- and third-generation antipsychotics have been
developed, in response to the identification of side effects such as extra pyramidal and metabolic side effects. Development of
new antipsychotics however, is not only due to a wish to avoid troublesome side effects, but due to a desire to target specific fea tures of schizophrenia
Citation
International Medical Journal Vol. 27, No. 4, pp. 433 - 437, August 2020
Type
Article