Myc/Bcl6 double hit lymphoma negative for T(3;8) Bcl6::Myc fusion Is associated with inferior survival, in contrast with T(3;8) positive pseudo‐double hit lymphoma
Maybury, B. D. James, L. Chadderton, N. Dowds, J. Venkatadasari, I. Riley, J. Qureshi, I. Talbot, G. Giles, H. V. Phillips, N. J.
Maybury, B. D.
James, L.
Chadderton, N.
Dowds, J.
Venkatadasari, I.
Riley, J.
Qureshi, I.
Talbot, G.
Giles, H. V.
Phillips, N. J.
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Affiliation
University Hospitals Birmingham NHS Foundation Trust; The Royal Wolverhampton NHS Trust; Worcestershire Acute Hospitals NHS Trust; University Hospitals of North Midlands NHS Trust; Walsall Healthcare NHS Trust; The Dudley Group Foundation Trust; Sandwell and West Birmingham NHS Trust; University Hospitals Coventry and Warwickshire; The Shrewsbury and Telford Hospital NHS Trust
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Publication date
2023-06
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Abstract
MYC/BCL6 DOUBLE HIT LYMPHOMA NEGATIVE FOR T(3;8) BCL6::MYC FUSION IS ASSOCIATED WITH INFERIOR SURVIVAL, IN CONTRAST WITH T(3;8) POSITIVE PSEUDO-DOUBLE HIT LYMPHOMA B Introduction: b A small proportion of large B cell non-Hodgkin lymphoma (NHL) has I MYC i and I BCL6 i rearrangements, detectable by fluorescence in-situ hybridisation (FISH) break-apart probes. Cases of I MYC/BCL2 i double-hit lymphoma without I BCL6 i rearrangement were excluded.
Citation
Maybury, BD, James, L, Chadderton, N, Dowds, J, Venkatadasari, I, Riley, J, Qureshi, I, Talbot, G, Giles, HV, Phillips, NJ, Gonzalez, MV, Rakesh, P, Haslam, A, Davies, D, Moosai, S, Lane, SA, Shenouda, A, Cherian, GV, Kaudlay, PK & Starczynski, J 2023, ‘Myc/Bcl6 Double Hit Lymphoma Negative for T(3;8) Bcl6::Myc Fusion Is Associated with Inferior Survival, in Contrast with T(3;8) Positive Pseudo‐Double Hit Lymphoma’, Hematological Oncology, vol. 41, pp. 205–207.
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Article