Evaluation of tumour infiltrating lymphocytes in luminal breast cancer using artificial intelligence.
Makhlouf, Shorouk Wahab, Noorul Toss, Michael Ibrahim, Asmaa Lashen, Ayat G Atallah, Nehal M Ghannam, Suzan Jahanifar, Mostafa Lu, Wenqi Graham, Simon
Makhlouf, Shorouk
Wahab, Noorul
Toss, Michael
Ibrahim, Asmaa
Lashen, Ayat G
Atallah, Nehal M
Ghannam, Suzan
Jahanifar, Mostafa
Lu, Wenqi
Graham, Simon
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2023-09-30
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Abstract
Background: Tumour infiltrating lymphocytes (TILs) are a prognostic parameter in triple-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC). However, their role in luminal (oestrogen receptor positive and HER2 negative (ER + /HER2-)) BC remains unclear. In this study, we used artificial intelligence (AI) to assess the prognostic significance of TILs in a large well-characterised cohort of luminal BC.
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Shorouk Makhlouf # 1 2, Noorul Wahab # 3, Michael Toss 1 4, Asmaa Ibrahim 1 5, Ayat G Lashen 1 6, Nehal M Atallah 1 6, Suzan Ghannam 1 7, Mostafa Jahanifar 3, Wenqi Lu 3, Simon Graham 3, Nigel P Mongan 8 9, Mohsin Bilal 3, Abhir Bhalerao 3, David Snead 10, Fayyaz Minhas 3, Shan E Ahmed Raza 3, Nasir Rajpoot 11, Emad Rakha 12 13 14
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Article