COVID-19 and cardiovascular disease in patients with chronic kidney disease
Del Vecchio, Lucia Balafa, Olga Dounousi, Evangelia Ekart, Robert Fernandez, Beatriz Fernandez Mark, Patrick B Sarafidis, Pantelis Valdivielso, Jose M Ferro, Charles J Mallamaci, Francesca
Del Vecchio, Lucia
Balafa, Olga
Dounousi, Evangelia
Ekart, Robert
Fernandez, Beatriz Fernandez
Mark, Patrick B
Sarafidis, Pantelis
Valdivielso, Jose M
Ferro, Charles J
Mallamaci, Francesca
Citations
Altmetric:
Affiliation
Other Contributors
Publication date
2023-09-28
Subject
Collections
Research Projects
Organizational Units
Journal Issue
Abstract
Millions of people worldwide have chronic kidney disease (CKD). Affected patients are at high risk for cardiovascular disease for several reasons. Among various comorbidities, CKD is associated with the more severe forms of SARS-Cov-2 infection. This is particularly true for patients receiving dialysis or for kidney recipients. From the start of the SARS-Cov-2 pandemic, several cardiovascular complications have been observed in affected subjects, spanning through acute inflammatory manifestations, cardiovascular events, thrombotic episodes and arrythmias. Several pathogenetic mechanisms have been hypothesized, including direct cytopathic viral effects on the myocardium, endothelial damage, and hypercoagulability. This spectrum of disease can occur during the acute phase of the infection, but also after months from recovery. This review is focussed on the cardiovascular complications of COVID-19 with particular interest to their implications for the CKD population.
Citation
Del Vecchio L, Balafa O, Dounousi E, Ekart R, Fernandez BF, Mark PB, Sarafidis P, Valdivielso JM, Ferro CJ, Mallamaci F. COVID-19 and cardiovascular disease in patients with chronic kidney disease. Nephrol Dial Transplant. 2024 Jan 31;39(2):177-189. doi: 10.1093/ndt/gfad170.
Type
Article