A case report of Clozapine-induced cardiomyopathy
Gourisaria, Gourav Sumanasan, Navin Ozen, Goksu Konduru, Thejas Swaroop Thozhuthumparambil, Karunakaran Pradeep
Gourisaria, Gourav
Sumanasan, Navin
Ozen, Goksu
Konduru, Thejas Swaroop
Thozhuthumparambil, Karunakaran Pradeep
Affiliation
Sandwell and West Birmingham NHS Trust; Royal Glamorgan Hospital
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Publication date
2025-06-30
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Abstract
Clozapine is an antipsychotic medication prescribed for patients who do not respond to or cannot tolerate standard antipsychotic treatments. It is also used to manage psychosis associated with Parkinson's disease. As a high-risk drug, clozapine requires strict monitoring. A rare but serious side effect is cardiomyopathy, which necessitates discontinuation of the medication. This report presents the case of a 42-year-old male patient admitted with recurrent falls and urinary sepsis while on clozapine. He exhibited persistent tachycardia and drowsiness and was diagnosed with cardiomyopathy, likely induced by clozapine.
Citation
Gourisaria G, Sumanasan N, Ozen G, Konduru TS, Karunakaran Thozhuthumparambil P. A Case Report of Clozapine-Induced Cardiomyopathy. Cureus. 2025 Jun 30;17(6):e87032. doi: 10.7759/cureus.87032
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Article