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Assessing heart disease using a novel magnetocardiography device
Beadle, Roger McDonnell, D Ghasemi-Roudsari, S Unitt, L Parker, S J Varcoe, B T H
Beadle, Roger
McDonnell, D
Ghasemi-Roudsari, S
Unitt, L
Parker, S J
Varcoe, B T H
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Affiliation
Department of Cardiology, South Warwickshire NHS Foundation Trust; Creavo Medical Technologies, Coventry; School of Physics and Astronomy, University of Leeds
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Publication date
2021-02-23
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Abstract
The aim of this paper is to present the use of a portable, unshielded magnetocardiograph (MCG) and identify key characteristics of MCG scans that could be used in future studies to identify parameters that are sensitive to cardiac pathology. We recruited 50 patients with confirmed myocardial infarction (MI) within the past 12 weeks and 46 volunteers with no history of cardiac disease. A set of 38 parameters were extracted from MCG features including both signals from the sensor array and from magnetic images obtained from the device and principal component analysis was used to concentrate the information contained in these parameters into uncorrelated predictors. Linear fits of these parameters were then used to examine the ability of MCG to distinguish between sub-groups of patients. In the first instance, the primary aim of this study was to ensure that MCG has a basic ability to separate a highly polarised patient group (young controls from post infarction patients) and to identify parameters that could be used in future studies to build a formal diagnostic tool kit. Parameters that parameterised left ventricular ejection fraction (LVEF) were identified and an example is presented to show differential low and high ejection fractions.
Citation
Beadle R, McDonnell D, Ghasemi-Roudsari S, Unitt L, Parker SJ, Varcoe BTH. Assessing heart disease using a novel magnetocardiography device. Biomed Phys Eng Express. 2021 Feb 23;7(2). doi: 10.1088/2057-1976/abe5c5. PMID: 33578399.
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Article