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    AboutPolicies Privacy NoticeBlack Country Healthcare NHS Foundation TrustCoventry and Warwickshire Partnership NHS TrustDudley Group NHS Foundation TrustGeorge Eliot Hospital NHS TrustSandwell and West Birmingham NHS TrustSouth Warwickshire University NHS Foundation TrustUniversity Hospitals Birmingham NHS Foundation TrustUniversity Hospitals Coventry and Warwickshire NHS TrustWalsall Healthcare NHS Trust

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    Carbon monoxide exposures reported to the UK National Poisons Information Service: a 4-year study.

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    Author
    Gentile, Daniela
    Adams, Richard
    Klatka, Michal
    Bradberry, Sally
    Gray, Laurence
    Thanacoody, Ruben
    Jackson, Gillian
    Sandilands, Euan A
    Affiliation
    National Poisons Information Service; Sandwell and West Birmingham NHS Trust; et al.
    Publication date
    2022-08-25
    Subject
    Clinical pathology
    
    Metadata
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    Abstract
    Background: Unintentional carbon monoxide (CO) poisoning poses a public health challenge. The UK National Poisons Information Service (NPIS) provides advice to healthcare professionals via the online database, TOXBASE®, and a 24-hour telephone line. Our aim was to analyse all CO-related enquiries to the NPIS. Methods: We analysed enquiries regarding unintentional CO exposure (1st July 2015-30th June 2019). Information on patient demographics, CO source and location, clinical features and poisoning severity was collected from telephone enquiries and TOXBASE accesses. Results: 2970 unintentional non-fire-related CO exposures were reported. Exposures occurred commonly in the home (60%) with faulty boilers frequently implicated (27.4%). Although five fatalities were reported, 68.7% of patients experienced no or minor symptoms only (headache most frequently reported). Despite being the gold standard measurement, blood carboxyhaemoglobin concentration was only recorded in 25.6% patients, with no statistically significant correlation with severity. Conclusions: Unintentional CO exposures in the UK commonly occur in domestic settings and although are generally of low severity, fatalities continue to occur. Carboxyhaemoglobin measurement is important to confirm exposure but further work is required to assess its validity as a prognostic indicator in CO exposure. Public health policy should continue to focus on raising awareness of the dangers of CO.
    Citation
    Gentile D, Adams R, Klatka M, Bradberry S, Gray L, Thanacoody R, Jackson G, Sandilands EA. Carbon monoxide exposures reported to the UK National Poisons Information Service: a 4-year study. J Public Health (Oxf). 2022 Aug 25;44(3):565-574. doi: 10.1093/pubmed/fdab132.
    Type
    Article
    Handle
    http://hdl.handle.net/20.500.14200/1049
    DOI
    10.1093/pubmed/fdab132
    PMID
    33993287
    Journal
    Journal of Public Health
    Publisher
    Oxford University Press
    ae974a485f413a2113503eed53cd6c53
    10.1093/pubmed/fdab132
    Scopus Count
    Collections
    Research (Articles)

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