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Volume maximised glycerol rhizolysis for trigeminal neuralgia: a single centre analysis of outcomes.

Goel, Aimee
Kulkarni, Girish
Cotici, Alexandru
Paluzzi, Alessandro
Hayton, Tom
Chelvarajah, Ramesh
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2023-05-05
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37 procedures were carried out for typical trigeminal neuralgia, 13 for secondary trigeminal neuralgia, and 3 for atypical trigeminal neuralgia. Overall, pain freedom was achieved in 85% cases, and 92% in patients with typical trigeminal neuralgia. Median duration of pain freedom in patients with typical trigeminal neuralgia was 63 months, versus 6 months in those with secondary trigeminal neuralgia (p < 0.00001). 14 procedures (26.4%) resulted in mild and temporary complications. 54.7% of cases experienced hypoaesthesia in a distribution similar to or less extensive than the distribution of trigeminal neuralgia. The presence of hypoaesthesia post-procedure was highly predictive of longer pain freedom (95 months versus 8 months median pain freedom (p = 0.00003)).
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Goel A, Kulkarni G, Cotici A, Paluzzi A, Hayton T, Chelvarajah R. Volume maximised glycerol rhizolysis for trigeminal neuralgia: a single centre analysis of outcomes. Br J Neurosurg. 2023 May 5:1-6. doi: 10.1080/02688697.2023.2207657. Epub ahead of print.
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