Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception.
Author
Dhillon-Smith, Rima KMiddleton, Lee J
Sunner, Kirandeep K
Cheed, Versha
Baker, Krys
Farrell-Carver, Samantha
Bender-Atik, Ruth
Agrawal, Rina
Bhatia, Kalsang
Edi-Osagie, Edmond
Gupta, Pratima
Jurkovic, Davor
Khalaf, Yacoub
MacLean, Marjory
McCabe, Christopher
Mulbagal, Khashia
Nunes, Natalie
Overton, Caroline
Rai, Raj
Raine-Fenning, Nick
Robinson, Lynne
Ross, Jackie
Sizer, Andrew
Small, Rachel
Tan, Alex
Underwood, Martyn
Kilby, Mark D
Boelaert, Kristien
Daniels, Jane
Thangaratinam, Shakila
Chan, Shiao Y
Coomarasamy, Arri
Quenby, Siobhan
Ghobara, Tarek
Publication date
2019-03-23Subject
Obstetrics. Midwifery
Metadata
Show full item recordAbstract
Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse outcomes.Citation
N Engl J Med . 2019 Apr 4;380(14):1316-1325Type
ArticlePMID
30907987Publisher
Massachusetts Medical Societyae974a485f413a2113503eed53cd6c53
10.1056/NEJMoa1812537