Reduced Cardiovascular Reserve in Chronic Kidney Failure: A Matched Cohort Study.

Ting, Stephen M S; Hamborg, Thomas; Oxborough, David; Lim, Kenneth; Koganti, Sudheer; Bland, Rosemary; Fletcher, Simon; Krishnan, Nithya S; Higgins, Robert M; Townend, Jonathan; Banerjee, Prithwish; imray, chris; Zehnder, Daniel; McGregor, Gordon; aldridge, nicolas

Abstract

Background: Patients with chronic kidney failure (CKF) experience impaired functional cardiovascular reserve with reduced oxygen consumption at peak exercise (VO(2peak)). No studies have examined whether this is related to impaired cardiovascular compliance as a consequence of loss of adaptive structural alterations, resulting from chronic uremia or hypertension.

Citation

Ting SM, Hamborg T, McGregor G, Oxborough D, Lim K, Koganti S, Aldridge N, Imray C, Bland R, Fletcher S, Krishnan NS, Higgins RM, Townend J, Banerjee P, Zehnder D. Reduced Cardiovascular Reserve in Chronic Kidney Failure: A Matched Cohort Study. Am J Kidney Dis. 2015 Aug;66(2):274-84. doi: 10.1053/j.ajkd.2015.02.335. Epub 2015 Apr 18.

Type

Article