Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child.

Author
Bromley, Rebecca
Adab, Naghme
Bluett-Duncan, Matt
Clayton-Smith, Jill
Christensen, Jakob
Edwards, Katherine
Greenhalgh, Janette
Hill, Ruaraidh A
Jackson, Cerian F
Khanom, Sonia
Publication date
2023-08-29
Subject
Neurology
Paediatrics
Obstetrics. Midwifery

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Abstract
Background: Prenatal exposure to certain anti-seizure medications (ASMs) is associated with an increased risk of major congenital malformations (MCM). The majority of women with epilepsy continue taking ASMs throughout pregnancy and, therefore, information on the potential risks associated with ASM treatment is required. Objectives: To assess the effects of prenatal exposure to ASMs on the prevalence of MCM in the child.
Citation
Cochrane Database Syst Rev . 2023 Aug 29;8(8):CD010224
Type
Evidence Summary
Handle
http://hdl.handle.net/20.500.14200/2116
Additional Links
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463554/
DOI
10.1002/14651858.CD010224.pub3
PMID
37647086
Journal
Cochrane Database of Systematic Reviews
Publisher
Wiley
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