COVID-19 and cardiovascular disease in patients with chronic kidney disease
Author
Del Vecchio, LuciaBalafa, Olga
Dounousi, Evangelia
Ekart, Robert
Fernandez, Beatriz Fernandez
Mark, Patrick B
Sarafidis, Pantelis
Valdivielso, Jose M
Ferro, Charles J
Mallamaci, Francesca
Publication date
2023-09-28
Metadata
Show full item recordAbstract
Millions of people worldwide have chronic kidney disease (CKD). Affected patients are at high risk for cardiovascular disease for several reasons. Among various comorbidities, CKD is associated with the more severe forms of SARS-Cov-2 infection. This is particularly true for patients receiving dialysis or for kidney recipients. From the start of the SARS-Cov-2 pandemic, several cardiovascular complications have been observed in affected subjects, spanning through acute inflammatory manifestations, cardiovascular events, thrombotic episodes and arrythmias. Several pathogenetic mechanisms have been hypothesized, including direct cytopathic viral effects on the myocardium, endothelial damage, and hypercoagulability. This spectrum of disease can occur during the acute phase of the infection, but also after months from recovery. This review is focussed on the cardiovascular complications of COVID-19 with particular interest to their implications for the CKD population.Citation
Del Vecchio L, Balafa O, Dounousi E, Ekart R, Fernandez BF, Mark PB, Sarafidis P, Valdivielso JM, Ferro CJ, Mallamaci F. COVID-19 and cardiovascular disease in patients with chronic kidney disease. Nephrol Dial Transplant. 2024 Jan 31;39(2):177-189. doi: 10.1093/ndt/gfad170.Type
ArticlePMID
37771078Publisher
Oxford University Pressae974a485f413a2113503eed53cd6c53
10.1093/ndt/gfad170