Renal artery stenting in the correct patients with atherosclerotic renovascular disease: time for a proper renal and cardiovascular outcome study?
Author
Theodorakopoulou, Marieta PKaragiannidis, Artemios G
Ferro, Charles J
Ortiz, Alberto
Sarafidis, Pantelis A
Publication date
2022-05-12
Metadata
Show full item recordAbstract
Atherosclerotic renovascular disease (ARVD) represents the most common type of renal artery stenosis. In the last decade, a few large trials failed to demonstrate the superiority of standard medical therapy plus percutaneous transluminal renal angioplasty (PTRA) compared with medical therapy alone in lowering blood pressure levels or preventing adverse renal and cardiovascular outcomes in patients with ARVD. However, this issue remains controversial and an ongoing debate focusses on the benefits that selected patients could experience from renal revascularization procedures. In this regard, several pieces of observational data show that PTRA is associated with future cardiorenal benefits in patients presenting with high-risk ARVD phenotypes. Such evidence resulted in a progressive shift in relevant recommendations, with most recent not-graded suggestions supporting that revascularization should be offered in these high-risk subjects. Existing evidence clearly calls for a properly designed randomized controlled trial with selected patients presenting high-risk ARVD phenotypes, in order to confirm the superiority of PTRA versus non-invasive management in this patient group and objectively guide everyday clinical practice.Citation
Theodorakopoulou MP, Karagiannidis AG, Ferro CJ, Ortiz A, Sarafidis PA. Renal artery stenting in the correct patients with atherosclerotic renovascular disease: time for a proper renal and cardiovascular outcome study? Clin Kidney J. 2022 May 12;16(2):201-204. doi: 10.1093/ckj/sfac140Type
ArticleAdditional Links
https://academic.oup.com/ckjPMID
36755839Journal
Clinical Kidney JournalPublisher
Oxford University Pressae974a485f413a2113503eed53cd6c53
10.1093/ckj/sfac140