Author
Shatila, MohamedHemead, Hanan
Murukesh, Nishanth
Taniere, Philippe
Russell, Caroline
Menon, Ashvini
Patel, Akshay J
Publication date
2023-11-09
Metadata
Show full item recordAbstract
Background: Thymic carcinomas are rare and aggressive tumours. They constitute a heterogeneous group of tumours with various histological patterns and subtypes resembling epithelial tumours arising from other organs. Case presentation: We hereby represent a case of primary thymic carcinoma with adenoid cystic carcinoma-like features (TCACC) which is an extremely rare variant of thymic adenocarcinoma. To date and to the best of our knowledge, there are nine reported cases in literature and ours is the tenth. Our case was treated surgically but the implementation of adjuvant chemoradiotherapy has been reported in few of the published cases. Conclusions: TCACC constitutes a rare entity of thymic adenocarcinoma with limited available literature. The current data is derived from few case reports and case series. The histological overlap of these tumours and primary ACC of salivary glands poses a diagnostic challenge. Radiological investigations, immunohistochemical phenotyping and genetic analysis are crucial in establishing the diagnosis.Citation
Shatila, M., Hemead, H., Murukesh, N., Taniere, P., Russell, C., Menon, A., & Patel, A. J. (2023). Adenoid cystic carcinoma of the thymus gland. Journal of cardiothoracic surgery, 18(1), 307. https://doi.org/10.1186/s13019-023-02432-wType
ArticleAdditional Links
https://cardiothoracicsurgery.biomedcentral.com/PMID
37946236Publisher
BMCae974a485f413a2113503eed53cd6c53
10.1186/s13019-023-02432-w