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Bone metastases from chondroblastoma: A rare pattern of metastatic disease in an adult

Murphy, Jennifer
Patel, Anish
Hughes, Simon
Rehousek, Petr
Drake, John
Sumathi, Vaiyapuri
Botchu, Rajesh
Mark Davies, A
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2023-11-07
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Chondroblastoma is a rare benign tumor, typically presenting in the first two decades. Systemic metastases in chondroblastoma are extremely rare and it is the rarity of these metastases which lead the World Health Organisation to re-classify this lesion from "intermediate" to "benign" in its updated classification of bone tumors in 2020. We present an unusual case of a 55 year-old male patient who presented with multiple FDG-avid bone lesions on a background of conventional chondroblastoma of the rib excised at another institution 11-years previously. Two of these lesions were also histologically-proven as conventional chondroblastoma at biopsy. This case highlights that, although rare, metastases can be seen in patients with chondroblastoma. To our knowledge, this is the only case with an unusual pattern of metastases limited to bone.
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Murphy J, Patel A, Hughes S, Rehousek P, Drake J, Sumathi V, Botchu R, Mark Davies A. Bone metastases from chondroblastoma: a rare pattern of metastatic disease in an adult. Skeletal Radiol. 2024 Jun;53(6):1219-1224. doi: 10.1007/s00256-023-04491-5. Epub 2023 Nov 7. Erratum in: Skeletal Radiol. 2024 Jun;53(6):1225. doi: 10.1007/s00256-023-04520-3.
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