Prolonged Zika virus RNA detection in semen of immunosuppressed patient

Author
Petridou, Christina
Bonsall, David
Ahmed, Aleem
Roberts, Mark
Bell, Carolyn
de Cesare, Mariateresa
Bowden, Rory
Graham, Victoria
Bailey, Daniel
Simpson, Andrew
Affiliation
Public Health England Porton, Salisbury; University of Oxford; Leicester Royal Infirmary; Worcestershire Royal Hospital; South Warwickshire University NHS Foundation Trust
Publication date
2019-08
Subject
Communicable diseases
Microbiology. Immunology

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Abstract
Zika virus RNA has been detected in semen samples collected <370 days after symptom onset. We report unusual persistence of Zika virus RNA in semen, confirmed by sequencing at 515 days after symptom onset and detectable for >900 days, in a patient with immunosuppression. Keywords: United Kingdom; Zika virus; clearance; immunosuppression; persistence; semen; viruses.
Citation
Petridou C, Bonsall D, Ahmed A, Roberts M, Bell C, de Cesare M, Bowden R, Graham V, Bailey D, Simpson A, Aarons E. Prolonged Zika Virus RNA Detection in Semen of Immunosuppressed Patient. Emerg Infect Dis. 2019 Aug;25(8):1598-1600. doi: 10.3201/eid2508.181543.
Type
Article
Handle
http://hdl.handle.net/20.500.14200/3213
Additional Links
http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6649331/
DOI
10.3201/eid2508.181543
PMID
31310210
Journal
Emerging Infectious Diseases
Publisher
Centers for Disease Control and Prevention
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